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非糖尿病患者中作为新冠感染后表现的上颌毛霉病性骨坏死:两例报告

Maxillary Mucormycotic Osteonecrosis as a Manifestation of Post-COVID-19 Infection in Non-diabetic Patients: Report of Two Cases.

作者信息

Paavai Thamizhanambi Tamizh, Vasanthi V, Rameshkumar Annasamy, Rajkumar Krishnan, Krishnakumar Raja V B, Muthusubramanian Veerabahu

机构信息

Department of Oral Pathology and Microbiology, SRM Dental College, Ramapuram, Chennai, Tamil Nadu, India.

Department of Oral and Maxillofacial Surgery, SRM Dental College, Ramapuram, Chennai, Tamil Nadu, India.

出版信息

J Microsc Ultrastruct. 2023 Nov 2;12(2):99-103. doi: 10.4103/jmau.jmau_81_23. eCollection 2024 Apr-Jun.

Abstract

Mucormycosis is a rare, opportunistic fungal infection prevalent in the elderly, especially in patients with uncontrolled diabetes or a compromised immune system. However, the outbreak of the pandemic declared by the World Health Organization in late 2019 increased the incidence of mucormycosis cases in COVID-19 patients due to increased steroid usage that resulted in an immunocompromised state. The current report presents two cases of oral mucormycotic osteomyelitis in patients who developed diabetes post-COVID infection, along with a review and relevant literature.

摘要

毛霉菌病是一种罕见的机会性真菌感染,在老年人中较为普遍,尤其是在糖尿病控制不佳或免疫系统受损的患者中。然而,世界卫生组织于2019年末宣布的大流行爆发,由于类固醇使用增加导致免疫功能低下状态,增加了COVID-19患者中毛霉菌病病例的发病率。本报告介绍了两例COVID感染后患上糖尿病的患者发生口腔毛霉菌性骨髓炎的病例,并对相关文献进行了综述。

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