特应性皮炎与肠道微生物群相关性的研究进展
Research Progress on the Correlation of Atopic Dermatitis with Gut Microbiota.
作者信息
Mao Qiuyu, Wang Xinyi, Cai Haibin, Yang Jingyi, Zhang Yiwen, Min Wei, Qian Qihong, Zeng Yibin
机构信息
Department of Dermatology, Minhang Hospital, Fudan University, Shanghai, People's Republic of China.
Department of Dermatology, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, People's Republic of China.
出版信息
Clin Cosmet Investig Dermatol. 2024 Jul 8;17:1613-1619. doi: 10.2147/CCID.S442551. eCollection 2024.
Abstract
Atopic dermatitis (AD) is a common skin disease, the pathogenesis of which has not been fully elucidated. The gut microbiota is the largest micro-ecosystem in the human body that affects the immune system and skin barrier function. Recent studies have shown that in addition to the environmental factors, skin barrier, genetic factors and immune response, gut microbiota disturbance may also cause AD. This review described the correlation of AD with gut microbiota and existing research status of AD treatment via targeting gut microbiota.
摘要
特应性皮炎（AD）是一种常见的皮肤病，其发病机制尚未完全阐明。肠道微生物群是人体中最大的影响免疫系统和皮肤屏障功能的微生态系统。最近的研究表明，除环境因素、皮肤屏障、遗传因素和免疫反应外，肠道微生物群紊乱也可能导致特应性皮炎。本文综述了特应性皮炎与肠道微生物群的相关性以及通过靶向肠道微生物群治疗特应性皮炎的现有研究状况。
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