Cui Xiuli, Xia Ronglin, Chao Aijun
Department of Osteo-Internal Medicine, Tianjin Hospital (Affiliated Hospital of Tianjin University) No. 406 Jiefang South Road, Hexi District, Tianjin 300211, China.
Am J Transl Res. 2024 Jun 15;16(6):2654-2661. doi: 10.62347/WKYA9182. eCollection 2024.
To examine the correlation between ABO blood type and the incidence of lower extremity deep vein thrombosis (LEDVT) in elderly patients after hip fracture surgery, while identifying contributing factors to thrombogenesis.
We conducted a retrospective analysis of 159 elderly patients with hip fractures treated at Tianjin Hospital (Affiliated Hospital of Tianjin University) from December 2021 to December 2023. The cohort was divided into two groups: those with O blood type (45 patients) and those with non-O blood types (114 patients). We analyzed clinical data and the incidence of LEDVT between the groups. Logistic regression was used to identify independent risk factors for LEDVT, and receiver operator characteristic (ROC) curve analysis evaluated the predictive efficacy of these factors.
The incidence of LEDVT was significantly higher in the non-O blood type group compared to the O blood type group (34.21% vs. 15.56%, P = 0.0408). Logistic regression identified high body mass index (BMI), comorbid hypertension, low platelet count (PLT), prolonged prothrombin time (PT), and non-O blood type as independent risk factors for LEDVT. The ROC curve for these predictors showed an area under the curve of 0.862, with a sensitivity of 75.22%, a specificity of 86.96%, and an accuracy of 78.62%.
ABO blood type is correlated with the occurrence of LEDVT in elderly patients' post-hip fracture. Those with non-O blood type, alongside other factors such as high BMI, hypertension, low PLT, and extended PT, are at increased risk of developing LEDVT.
探讨老年髋部骨折患者术后ABO血型与下肢深静脉血栓形成（LEDVT）发生率之间的相关性，并确定血栓形成的相关因素。
对2021年12月至2023年12月在天津医院（天津大学附属）接受治疗的159例老年髋部骨折患者进行回顾性分析。该队列分为两组：O型血患者（45例）和非O型血患者（114例）。我们分析了两组之间的临床数据和LEDVT的发生率。采用逻辑回归分析确定LEDVT的独立危险因素，并通过受试者工作特征（ROC）曲线分析评估这些因素的预测效能。
非O型血组LEDVT的发生率显著高于O型血组（34.21%对15.56%，P = 0.0408）。逻辑回归分析确定高体重指数（BMI）、合并高血压、低血小板计数（PLT）、凝血酶原时间（PT）延长和非O型血为LEDVT的独立危险因素。这些预测指标的ROC曲线下面积为0.862，灵敏度为75.22%，特异度为86.96%，准确度为78.62%。
ABO血型与老年髋部骨折患者LEDVT的发生相关。非O型血患者以及高BMI、高血压、低PLT和PT延长等其他因素会增加发生LEDVT的风险。
