青蒿素诱导的胆汁淤积性肝损伤和肝内胆管减少症。
Artemisinin-induced cholestatic liver injury and intrahepatic ductopenia.
作者信息
Thio Joel, Haig Adam, Swe Ei Phyu Phyu, Nguyen Paul, Tran Kayla, Kasi Madhavi
机构信息
Department of Gastroenterology, The Prince Charles Hospital, 627 Rode Road, Brisbane, Queensland 4032, Australia.
Faculty of Medicine, University of Queensland, Mayne Medical School, 20 Weightman St, Brisbane, Queensland 4006, Australia.
出版信息
Oxf Med Case Reports. 2024 Jul 13;2024(7):omae070. doi: 10.1093/omcr/omae070. eCollection 2024 Jul.
Artemisinin, an ancient Chinese herbal remedy known colloquially as "Qinghao", is now used as treatment for malaria as recommended by the World Health Organisation. There have been few reports of artemisinin-induced liver injury. Most of these instances of hepatotoxicity are reportedly due to prolonged use of herbal remedies containing artemisinin. To our knowledge, we report the first case of intrahepatic ductopenia in a patient with cholestatic liver injury after artemisinin use.
青蒿素，一种俗称“青蒿”的古老的中国草药疗法，现在被世界卫生组织推荐用于治疗疟疾。关于青蒿素引起肝损伤的报道很少。据报道，这些肝毒性病例大多是由于长期使用含青蒿素的草药疗法所致。据我们所知，我们报告了首例使用青蒿素后出现胆汁淤积性肝损伤并伴有肝内胆管减少的病例。
Zotero 插件