Kitamura Naoya, Tanabe Keitaro, Ojima Toshihiro, Shimoyama Koichiro, Noguchi Akira, Hirabayashi Kenichi, Tsuchiya Tomoshi
Department of Thoracic Surgery Toyama University Hospital Toyama Japan.
Department of Diagnostic Pathology Toyama University Hospital Toyama Japan.
Respirol Case Rep. 2024 Jul 14;12(7):e01417. doi: 10.1002/rcr2.1417. eCollection 2024 Jul.
Lymphoid follicular hyperplasia (LFH) is a benign lymphoproliferative disease. Although it can occur within the thoracic cavity, LFH originating from the chest wall has not been reported. A 79-year-old woman was incidentally found to have a well-defined mass on the left posterior chest wall during a preoperative examination for aortic valve replacement. The mass had slowly grown over 6 years. Thoracoscopic surgical resection was performed without complications. Pathological examination ruled out lymphoproliferative diseases, such as Castleman disease or malignant lymphoma, and a diagnosis of LFH was made. Although LFH generally has a good prognosis, surgical resection is recommended for diagnostic and therapeutic purposes owing to the possibility of malignancy masquerading as a reactive lesion. This is the first report of an LFH arising from the chest wall with imaging findings similar to other benign tumours. Its potential as a differential diagnosis for tumours with similar imaging findings is highlighted.
淋巴滤泡性增生（LFH）是一种良性淋巴增殖性疾病。尽管它可发生于胸腔内，但起源于胸壁的LFH尚未见报道。一名79岁女性在进行主动脉瓣置换术前检查时偶然发现左后胸壁有一个边界清晰的肿块。该肿块在6年中缓慢生长。进行了胸腔镜手术切除，无并发症。病理检查排除了如Castleman病或恶性淋巴瘤等淋巴增殖性疾病，诊断为LFH。尽管LFH一般预后良好，但由于存在恶性病变伪装成反应性病变的可能性，建议进行手术切除以用于诊断和治疗目的。这是首例起源于胸壁且影像学表现与其他良性肿瘤相似的LFH报告。强调了其作为具有相似影像学表现肿瘤的鉴别诊断的可能性。
