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聚乙醇酸910(薇乔)在鼻腔内自然脱落的时间。

The Time to Spontaneous Drop of Polyglactin 910 (Vicryl) in the Nasal Cavity.

作者信息

Hemmi Tomotaka, Nomura Kazuhiro, Omura Kazuhiro, Takeda Teppei, Sugawara Mitsuru, Ikeda Ryoukichi

机构信息

Otolaryngology, Tohoku Kosai Hospital, Sendai, JPN.

Otolaryngology, Head and Neck Surgery, The Jikei University School of Medicine, Tokyo, JPN.

出版信息

Cureus. 2024 Jun 13;16(6):e62335. doi: 10.7759/cureus.62335. eCollection 2024 Jun.

Abstract

Sutures play a crucial role in closing mucosal incisions during endoscopic nasal surgery. The duration until the spontaneous drop of polyglactin 910 (Vicryl) sutures in the nasal cavity remains uncertain. To investigate this, we examined the medical records of patients who underwent septoplasty, inferior turbinate reduction, or endoscopic modified medial maxillectomy with polyglactin 910 sutures. The sutures were counted and monitored during follow-up visits, and removal occurred only if patients reported discomfort. In our study of 124 patients, a total of 453 sutures were placed during surgery. Eighteen sutures had to be intentionally removed due to discomfort. Importantly, no surgical site infections were observed during the follow-up period. We found that sutures on the lateral nasal wall persisted longer than those on the nasal septum, with respective half-lives of 70 days and 64 days (p = 0.0071). In conclusion, using polyglactin 910 sutures in nasal surgery and allowing them to dissolve naturally in the submucosa is an effective approach. The sutures exhibit longer persistence on the lateral nasal wall compared to the nasal septum.

摘要

缝线在内镜鼻腔手术中对闭合黏膜切口起着至关重要的作用。聚乙醇酸910(薇乔)缝线在鼻腔内自然脱落的时间仍不确定。为了对此进行研究,我们检查了接受鼻中隔成形术、下鼻甲切除术或内镜改良上颌骨内侧切除术并使用聚乙醇酸910缝线的患者的病历。在随访期间对缝线进行计数和监测,只有在患者报告不适时才进行拆除。在我们对124例患者的研究中,手术期间共放置了453根缝线。由于不适,有18根缝线不得不被有意拆除。重要的是,在随访期间未观察到手术部位感染。我们发现,鼻侧壁上的缝线比鼻中隔上的缝线存留时间更长,其半衰期分别为70天和64天(p = 0.0071)。总之,在鼻腔手术中使用聚乙醇酸910缝线并使其在黏膜下层自然溶解是一种有效的方法。与鼻中隔相比,缝线在鼻侧壁上的存留时间更长。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/709b/11246194/4983ddce2dab/cureus-0016-00000062335-i01.jpg

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