Zhang Le, Bi Yan, Qi Min, Fu Xu-Wen, Wei Jia-Lu, Gan Wei, Zhu Long, Li Xiang, Bai Jin-Song
Department of ICU, Kunming Third People's Hospital/Yunnan Clinical Medical Center for Infectious Diseases, Kunming, 650041, Yunnan, China.
Department of Radiology, The People's Hospital of Lincang, Lincang, 677000, China.
Open Med (Wars). 2024 Jul 11;19(1):20240996. doi: 10.1515/med-2024-0996. eCollection 2024.
The aim of this study was to investigate the role of the Hounsfield unit value of chest CT non-contrast enhanced scan in evaluating the severity of anemia in HIV-infected patients.
Patients with HIV infection combined with anemia admitted to the Kunming Third People's Hospital were retrospectively collected and divided into mild anemia, moderate anemia, and severe anemia groups by peripheral hemoglobin (HB) content and calculated the ratio of ventricular septum density (VSD) to left ventricular density (LVD) and VSD to right ventricular density (RVD); then, the above patients were divided into the critical value group and the non-critical value group according to HB and compared the differences of LVD, RVD, VSD/LVD, and VSD/RVD in the two groups of patients.
A total of 126 patients were included, with a mean age of 47.9 ± 11.1 years; 43 cases were in the mild anemia group, 59 cases were in the moderate anemia group, and 24 cases were in the severe anemia group; the differences in LVD, RVD, VSD/LVD, and VSD/RVD were significant in the three groups; VSD/LVD was an independent predictor for the diagnosis of anemia critical value in the non-critical value group vs critical value group by multifactorial binary logistic regression analysis, and the ROC was plotted using VSD/LVD with an area under the curve of 0.731.
The measurement of cardiac cavity density and ventricular septal density under CT plain film scan has a high accuracy in evaluating the severity of anemia in patients with HIV infection and can quickly determine the severity of HIV infection in the early stage and treat it as soon as possible.
本研究旨在探讨胸部CT平扫的亨氏单位值在评估HIV感染患者贫血严重程度中的作用。
回顾性收集昆明市第三人民医院收治的HIV感染合并贫血患者，根据外周血红蛋白（HB）含量分为轻度贫血、中度贫血和重度贫血组，并计算室间隔密度（VSD）与左心室密度（LVD）的比值以及VSD与右心室密度（RVD）的比值；然后，根据HB将上述患者分为临界值组和非临界值组，比较两组患者LVD、RVD、VSD/LVD和VSD/RVD的差异。
共纳入126例患者，平均年龄47.9±11.1岁；轻度贫血组43例，中度贫血组59例，重度贫血组24例；三组患者的LVD、RVD、VSD/LVD和VSD/RVD差异有统计学意义；多因素二元逻辑回归分析显示，在非临界值组与临界值组中，VSD/LVD是诊断贫血临界值的独立预测因素，以VSD/LVD绘制ROC曲线，曲线下面积为0.731。
CT平扫测量心腔密度和室间隔密度对评估HIV感染患者贫血严重程度具有较高的准确性，可在早期快速判断HIV感染严重程度并尽早治疗。
