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一名25岁患有科根综合征的患者发生前壁ST段抬高型心肌梗死。

Anterior STEMI in a 25-year-old with Cogan syndrome.

作者信息

Takla Andrew, Eid Fahad, Eid Mohamed Magdi, Joshi Akshay, Abtahian Farhad, Cheng Allen, Feitell Scott

机构信息

Department of Internal Medicine, Rochester General Hospital, Rochester, NY, USA.

Department of Internal Medicine, Unity Hospital, Rochester, NY, USA.

出版信息

J Cardiol Cases. 2024 Mar 5;30(1):9-11. doi: 10.1016/j.jccase.2024.02.014. eCollection 2024 Jul.

DOI:10.1016/j.jccase.2024.02.014
PMID:39007044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11245749/
Abstract

UNLABELLED

Cogan syndrome (CS) is a chronic inflammatory disorder primarily affecting young adults. It is characterized by interstitial keratitis, vestibuloauditory dysfunction, and, rarely, systemic vasculitis and aortitis. In this case report, we present a rare instance of a young male with anterior ST-elevation myocardial infarction in the context of aneurysmal coronary vessels and proximal occlusion of the left anterior descending artery. This case underscores the importance of recognizing cardiac risk factors in the setting of CS, as they can be life-threatening. Regular follow up is necessary, especially for patients showing signs of vasculitis or experiencing cardiac symptoms. A multidisciplinary approach to management can help optimize the prognosis for these complex patients.

LEARNING OBJECTIVE

Comprehend Cogan syndrome (CS): Grasp the clinical manifestations and potential cardiovascular complications of CS. Diagnostic approach in CS: Differentiate cardiac symptoms in CS from typical coronary diseases, emphasizing the role of heart catheterization. Multidisciplinary management: Recognize the importance of integrating rheumatologists, cardiologists, and surgeons for optimal CS patient outcomes.

摘要

未标注

科根综合征(CS)是一种主要影响年轻人的慢性炎症性疾病。其特征为间质性角膜炎、前庭听觉功能障碍,以及罕见的系统性血管炎和主动脉炎。在本病例报告中,我们呈现了一例罕见的年轻男性病例,该患者在患有冠状动脉瘤和左前降支近端闭塞的情况下发生了前壁ST段抬高型心肌梗死。本病例强调了在CS背景下识别心脏危险因素的重要性,因为它们可能危及生命。定期随访是必要的,特别是对于出现血管炎迹象或有心脏症状的患者。多学科管理方法有助于优化这些复杂患者的预后。

学习目标

了解科根综合征(CS):掌握CS的临床表现和潜在的心血管并发症。CS的诊断方法:区分CS中的心脏症状与典型冠状动脉疾病,强调心导管检查的作用。多学科管理:认识到整合风湿病学家、心脏病学家和外科医生对CS患者实现最佳治疗效果的重要性。

相似文献

1
Anterior STEMI in a 25-year-old with Cogan syndrome.一名25岁患有科根综合征的患者发生前壁ST段抬高型心肌梗死。
J Cardiol Cases. 2024 Mar 5;30(1):9-11. doi: 10.1016/j.jccase.2024.02.014. eCollection 2024 Jul.
2
Cogan syndrome: studies in thirteen patients, long-term follow-up, and a review of the literature.科根综合征:13例患者的研究、长期随访及文献综述
Medicine (Baltimore). 1980 Nov;59(6):426-41.
3
Cogan syndrome: a retrospective review of 60 patients throughout a half century.科根综合征:半个世纪以来60例患者的回顾性研究
Mayo Clin Proc. 2006 Apr;81(4):483-8. doi: 10.4065/81.4.483.
4
Atypical Cogan's syndrome associated with coronary disease.与冠状动脉疾病相关的非典型 Cogan 综合征。
Chin Med J (Engl). 2011 Oct;124(19):3192-4.
5
Acute Limb Ischemia in Cogan Syndrome.Cogan 综合征的急性肢体缺血。
Am J Case Rep. 2022 Apr 30;23:e935929. doi: 10.12659/AJCR.935929.
6
A Case of ST-Elevation Myocardial Infarction With Right Bundle Branch Block, an Ominous Sign of Critical Coronary Occlusion.一例伴有右束支传导阻滞的ST段抬高型心肌梗死,冠状动脉严重闭塞的不祥征兆。
Cureus. 2022 Jan 13;14(1):e21216. doi: 10.7759/cureus.21216. eCollection 2022 Jan.
7
Cogan's syndrome: a cause of progressive hearing deafness.科根综合征:进行性听力丧失的一个病因。
Am J Otolaryngol. 2006 Jan-Feb;27(1):68-70. doi: 10.1016/j.amjoto.2005.07.006.
8
Successful full-term pregnancy in a woman with Cogan's syndrome: a case report.
Clin Rheumatol. 2007 Dec;26(12):2181-2183. doi: 10.1007/s10067-007-0664-4. Epub 2007 Jun 16.
9
Hepatic vasculitis mimicking multiple liver abscesses in Cogan's Syndrome.科根综合征中酷似多发性肝脓肿的肝血管炎
Acta Reumatol Port. 2019 Jul 8.
10
Cogan syndrome: An autoimmune eye and ear disease with systemic manifestations.Cogan 综合征:一种具有全身表现的自身免疫性眼耳疾病。
Natl Med J India. 2019 Nov-Dec;32(6):349-351. doi: 10.4103/0970-258X.303611.

本文引用的文献

1
Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association.川崎病的诊断、治疗和长期管理:美国心脏协会发布的一份面向医疗保健专业人员的科学声明。
Circulation. 2017 Apr 25;135(17):e927-e999. doi: 10.1161/CIR.0000000000000484. Epub 2017 Mar 29.
2
Cogan syndrome--pathogenesis, clinical variants and treatment approaches.Cogan 综合征——发病机制、临床变异型和治疗方法。
Autoimmun Rev. 2014 Apr-May;13(4-5):351-4. doi: 10.1016/j.autrev.2014.01.002. Epub 2014 Jan 10.
3
Cogan's syndrome: an autoimmune inner ear disease.科根综合征:一种自身免疫性内耳疾病。
Autoimmun Rev. 2013 Jan;12(3):396-400. doi: 10.1016/j.autrev.2012.07.012. Epub 2012 Jul 28.
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Cogan's syndrome with left main coronary artery occlusion.伴有左侧主干冠状动脉闭塞的柯根氏综合征。
Cardiol J. 2009;16(6):573-6.
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Aortitis.主动脉炎
Circulation. 2008 Jun 10;117(23):3039-51. doi: 10.1161/CIRCULATIONAHA.107.760686.
6
Cogan syndrome: a retrospective review of 60 patients throughout a half century.科根综合征:半个世纪以来60例患者的回顾性研究
Mayo Clin Proc. 2006 Apr;81(4):483-8. doi: 10.4065/81.4.483.
7
Active remodeling of the coronary arterial lesions in the late phase of Kawasaki disease: immunohistochemical study.川崎病晚期冠状动脉病变的活性重塑:免疫组织化学研究
Circulation. 2000 Jun 27;101(25):2935-41. doi: 10.1161/01.cir.101.25.2935.
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Cogan syndrome: studies in thirteen patients, long-term follow-up, and a review of the literature.科根综合征:13例患者的研究、长期随访及文献综述
Medicine (Baltimore). 1980 Nov;59(6):426-41.