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一名25岁患有科根综合征的患者发生前壁ST段抬高型心肌梗死。

Anterior STEMI in a 25-year-old with Cogan syndrome.

作者信息

Takla Andrew, Eid Fahad, Eid Mohamed Magdi, Joshi Akshay, Abtahian Farhad, Cheng Allen, Feitell Scott

机构信息

Department of Internal Medicine, Rochester General Hospital, Rochester, NY, USA.

Department of Internal Medicine, Unity Hospital, Rochester, NY, USA.

出版信息

J Cardiol Cases. 2024 Mar 5;30(1):9-11. doi: 10.1016/j.jccase.2024.02.014. eCollection 2024 Jul.

Abstract

UNLABELLED

Cogan syndrome (CS) is a chronic inflammatory disorder primarily affecting young adults. It is characterized by interstitial keratitis, vestibuloauditory dysfunction, and, rarely, systemic vasculitis and aortitis. In this case report, we present a rare instance of a young male with anterior ST-elevation myocardial infarction in the context of aneurysmal coronary vessels and proximal occlusion of the left anterior descending artery. This case underscores the importance of recognizing cardiac risk factors in the setting of CS, as they can be life-threatening. Regular follow up is necessary, especially for patients showing signs of vasculitis or experiencing cardiac symptoms. A multidisciplinary approach to management can help optimize the prognosis for these complex patients.

LEARNING OBJECTIVE

Comprehend Cogan syndrome (CS): Grasp the clinical manifestations and potential cardiovascular complications of CS. Diagnostic approach in CS: Differentiate cardiac symptoms in CS from typical coronary diseases, emphasizing the role of heart catheterization. Multidisciplinary management: Recognize the importance of integrating rheumatologists, cardiologists, and surgeons for optimal CS patient outcomes.

摘要

未标注

科根综合征(CS)是一种主要影响年轻人的慢性炎症性疾病。其特征为间质性角膜炎、前庭听觉功能障碍,以及罕见的系统性血管炎和主动脉炎。在本病例报告中,我们呈现了一例罕见的年轻男性病例,该患者在患有冠状动脉瘤和左前降支近端闭塞的情况下发生了前壁ST段抬高型心肌梗死。本病例强调了在CS背景下识别心脏危险因素的重要性,因为它们可能危及生命。定期随访是必要的,特别是对于出现血管炎迹象或有心脏症状的患者。多学科管理方法有助于优化这些复杂患者的预后。

学习目标

了解科根综合征(CS):掌握CS的临床表现和潜在的心血管并发症。CS的诊断方法:区分CS中的心脏症状与典型冠状动脉疾病,强调心导管检查的作用。多学科管理:认识到整合风湿病学家、心脏病学家和外科医生对CS患者实现最佳治疗效果的重要性。

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本文引用的文献

2
Cogan syndrome--pathogenesis, clinical variants and treatment approaches.Cogan 综合征——发病机制、临床变异型和治疗方法。
Autoimmun Rev. 2014 Apr-May;13(4-5):351-4. doi: 10.1016/j.autrev.2014.01.002. Epub 2014 Jan 10.
3
Cogan's syndrome: an autoimmune inner ear disease.科根综合征:一种自身免疫性内耳疾病。
Autoimmun Rev. 2013 Jan;12(3):396-400. doi: 10.1016/j.autrev.2012.07.012. Epub 2012 Jul 28.
5
Aortitis.主动脉炎
Circulation. 2008 Jun 10;117(23):3039-51. doi: 10.1161/CIRCULATIONAHA.107.760686.

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