Watanabe Shingo, Kano Yuya, Masuda Ryo, Usui Michio
Department of Cardiology, Tokyo Yamate Medical Center, Tokyo, Japan.
J Cardiol Cases. 2024 Mar 5;30(1):1-4. doi: 10.1016/j.jccase.2024.02.010. eCollection 2024 Jul.
It has been reported that patients with moyamoya disease have a high prevalence of coronary artery disease. On the other hand, the pathology of coronary artery disease is not fully understood. We were able to evaluate vascular properties using optical coherence tomography in a case of acute myocardial infarction that occurred in a relatively young woman with moyamoya disease. Previous reports using intravascular ultrasound have shown that coronary artery lesions in patients with moyamoya disease are caused by fibrous cell proliferation. Optical coherence tomography of our case showed a fibrous plaque rich in macrophages and a lipidic plaque. We believe that our case may lead to elucidation of the etiology of coronary artery disease in patients with moyamoya disease.
It is known that patients with moyamoya disease develop coronary artery disease at a young age, but the etiology has not been clarified. We used optical coherence tomography to evaluate the intravascular conditions of coronary artery disease patients with moyamoya disease. The lesions of coronary artery disease associated with moyamoya disease were mainly arteriosclerotic lesions rich in inflammation.
据报道,烟雾病患者冠状动脉疾病的患病率较高。另一方面,冠状动脉疾病的病理尚未完全明了。我们能够在一名患有烟雾病的相对年轻女性发生急性心肌梗死的病例中,使用光学相干断层扫描来评估血管特性。先前使用血管内超声的报告显示,烟雾病患者的冠状动脉病变是由纤维细胞增殖引起的。我们病例的光学相干断层扫描显示出富含巨噬细胞的纤维斑块和脂质斑块。我们认为我们的病例可能有助于阐明烟雾病患者冠状动脉疾病的病因。
已知烟雾病患者在年轻时就会患冠状动脉疾病,但其病因尚未阐明。我们使用光学相干断层扫描来评估患有烟雾病的冠状动脉疾病患者的血管内状况。与烟雾病相关的冠状动脉疾病病变主要是富含炎症的动脉粥样硬化病变。