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内镜第三脑室造瘘术和单一入路松果体活检。

Endoscopic Third Ventriculostomy and Pineal Biopsy from a Single Entry Point.

机构信息

Department of Neurosurgery, Istanbul University Faculty of Medicine;

Department of Neurosurgery, Istanbul University Faculty of Medicine.

出版信息

J Vis Exp. 2024 Jun 28(208). doi: 10.3791/66837.

Abstract

Pineal neoplasms have a significant impact on children although they are relatively uncommon. They account for approximately 3-11% of all childhood brain tumors, which is considerably higher than the <1% seen in adult brain tumors. These tumors can be divided into three main categories: germ cell tumors, parenchymal pineal tumors, and tumors arising from related anatomical structures. Obtaining an accurate and minimally invasive tissue diagnosis is crucial for selecting the most appropriate treatment regimen for patients with pineal gland tumors. This is due to the diverse treatment options available and the potential risks associated with complete resection. In cases where patients present with acute obstructive hydrocephalus caused by a pineal gland tumor, immediate treatment of the hydrocephalus is necessary. The urgency stems from the potential complications of hydrocephalus, including increased intracranial pressure and neurological deficits. To address these challenges, a minimally invasive endoscopic approach provides a valuable opportunity. This technique allows clinicians to promptly relieve hydrocephalus and obtain a histological diagnosis simultaneously. This dual benefit enables a more comprehensive understanding of the tumor and assists in determining the most effective treatment strategy for the patient.

摘要

松果体肿瘤虽然相对少见,但对儿童有重大影响。它们约占所有儿童脑肿瘤的 3-11%,明显高于成人脑肿瘤中 <1%的比例。这些肿瘤可以分为三大类:生殖细胞瘤、松果体实质肿瘤和源自相关解剖结构的肿瘤。获得准确和微创的组织诊断对于为松果体肿瘤患者选择最合适的治疗方案至关重要。这是因为有多种治疗选择,而且完全切除存在潜在风险。如果患者因松果体肿瘤出现急性梗阻性脑积水,需要立即治疗脑积水。这种紧迫性源于脑积水的潜在并发症,包括颅内压升高和神经功能缺损。为了应对这些挑战,微创内镜方法提供了一个有价值的机会。该技术使临床医生能够迅速缓解脑积水并同时获得组织学诊断。这种双重获益使我们能够更全面地了解肿瘤,并有助于确定患者最有效的治疗策略。

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