Department of Internal Medicine, Division of Endocrinology & Metabolism, Istanbul University, Istanbul Faculty of Medicine, Istanbul, 34093, Turkey.
Department of Medical Statistics, Istanbul University, Istanbul Faculty of Medicine, Istanbul, 34093,Turkey.
Biomark Med. 2024;18(9):459-467. doi: 10.1080/17520363.2024.2342240. Epub 2024 May 24.
The role of severity and duration of inflammatory findings on the development of persistent hypothyroidism and anemia has not been clarified in subacute thyroiditis (SAT). Demographic data and laboratory parameters of patients with SAT were analyzed retrospectively. Permanent hypothyroidism was observed in 28.1% of patients. Baseline elevated erythrocyte sedimentation rate as defined >74.5 mm/h was found to be associated with permanent hypothyroidism, but the duration of inflammation was not different between the recovered and hypothyroid patients. Baseline hemoglobin values improved without specific therapy in 3.5 months. The initial severity but not the duration of inflammation increases the risk for the development of permanent thyroid dysfunction, and anemia improves with the resolution of inflammation.
亚急性甲状腺炎（SAT）患者中，炎症严重程度和持续时间与持续性甲状腺功能减退症和贫血的发展之间的关系尚未阐明。本研究回顾性分析了 SAT 患者的人口统计学数据和实验室参数。28.1%的患者发生永久性甲状腺功能减退症。基线红细胞沉降率升高（定义为>74.5mm/h）与永久性甲状腺功能减退症相关，但恢复期和甲状腺功能减退症患者的炎症持续时间无差异。在 3.5 个月内，未接受特殊治疗的情况下，血红蛋白基线值有所改善。炎症初始严重程度而非持续时间增加永久性甲状腺功能障碍的风险，且贫血随炎症消退而改善。
