Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Science, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, No. 1 Dong Jiao Min Xiang Street, Dongcheng District, Beijing, 100730, China.
Graefes Arch Clin Exp Ophthalmol. 2024 Dec;262(12):4013-4016. doi: 10.1007/s00417-024-06572-0. Epub 2024 Jul 15.
To compare the surgical effectiveness and safety of phacoemulsification combined with KDB (Phaco-KDB) and with Trabectome (Phaco-Trabectome) at 6 months follow-up in patients with open-angle glaucoma (OAG) METHODS: This comparative case series was conducted at Beijing Tongren Hospital, including patients diagnosed with OAG who underwent Phaco-KDB from November 2021 to April 2022 and Phaco-Trabectome from April 2017 to December 2017. Surgical success was defined as an IOP reduction ≥ 20% or a postoperative IOP ≤ 21 mmHg. Kaplan-Meier methods were used to calculate cumulative rates of success among groups RESULTS: A total of 35 eyes from 29 patients were included in the analysis. At 6-month, Both groups exhibited a significant reduction in IOP and the number of IOP-lowering medications compared to preoperative (P=0.01 and P<0.01, respectively). There were no significant differences among groups in terms of reducing IOP and the number of IOP-lowering medications (all P values<0.05). In the Phaco-KDB and Phaco-Trabectome groups, 53.8% and 45.0% of patients achieved an IOP reduction of ≥ 20%, while 92.3% and 85% achieved a mean IOP ≤ 21 mmHg 6 months after surgery. The incidence of IOP spike was 20%, and 3 eyes (8.6%) needed further surgery to control the IOP CONCLUSIONS: Both Phaco-KDB and Phaco-Trabectome demonstrate a significant reduction in IOP and the number of IOP-lowering medications. Phaco-Trabectome appears to provide a more predictable postoperative course in the early postoperative period compared to Phaco-KDB, and the postoperative mean IOP is lower in Phaco-KDB compared to Phaco-Trabectome, despite not being statistically significant.
比较超声乳化白内障吸除术联合巩膜KDB 切除术（Phaco-KDB）和小梁切除术（Phaco-Trabectome）在开角型青光眼（OAG）患者中的 6 个月随访时的手术效果和安全性。方法：这是一项在北京同仁医院进行的病例系列对照研究，纳入了 2021 年 11 月至 2022 年 4 月期间接受 Phaco-KDB 手术和 2017 年 4 月至 2017 年 12 月期间接受 Phaco-Trabectome 手术的 OAG 患者。手术成功定义为眼压降低≥20%或术后眼压≤21mmHg。采用 Kaplan-Meier 方法计算各组的累积成功率。结果：共纳入 29 例患者的 35 只眼。在 6 个月时，两组眼压均较术前显著降低，且使用降眼压药物的数量均显著减少（P=0.01 和 P<0.01）。两组在降低眼压和使用降眼压药物的数量方面无显著差异（P 值均<0.05）。在 Phaco-KDB 组和 Phaco-Trabectome 组中，53.8%和 45.0%的患者眼压降低≥20%，92.3%和 85%的患者术后 6 个月时平均眼压≤21mmHg。眼压升高的发生率为 20%，3 只眼（8.6%）需要进一步手术控制眼压。结论：Phaco-KDB 和 Phaco-Trabectome 均可显著降低眼压和使用降眼压药物的数量。与 Phaco-KDB 相比，Phaco-Trabectome 在术后早期提供了更可预测的术后过程，并且术后平均眼压在 Phaco-KDB 组中低于 Phaco-Trabectome 组，但差异无统计学意义。
