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[术后胸骨纵隔炎:病变形态、治疗策略]

[Postoperative sternomediastinitis: morphology of lesion, treatment strategy].

作者信息

Vinokurov I A, Belov Yu V, Tagabilev D G, Yusupov S A

机构信息

Petrovsky National Research Center of Surgery, Moscow, Russia.

Sechenov First Moscow State Medical University, Moscow, Russia.

出版信息

Khirurgiia (Mosk). 2024(7):78-84. doi: 10.17116/hirurgia202407178.

Abstract

OBJECTIVE

To analyze bone tissue damage at different stages of disease (El Oakley classification), treatment options for each clinical situation and results after each approach.

MATERIAL AND METHODS

There were 45 patients with wound complications after cardiac surgery between October 2022 and September 2023. Thirty-eight (84.4%) patients underwent CABG, 7 (15.6%) patients - heart valve or aortic surgery. Mean age of patients was 68.1±10.3 years. There were 35 men (77.8%) and 10 women (22.2%). The first type was found in 11 (24.5%) patients, type 2-3 - 19 (42.2%), type 4 - 4 (8.8%), type 5 - 11 (24.5%) patients.

RESULTS

Systemic inflammatory response syndrome was observed in 7 (36.8%) persons of the 1 group, 14 (73.7%) ones of the 2 group, 4 (100%) patients of the 3 group and 2 (18.2%) patients of the 4 group. C-reactive protein and procalcitonin increased in all patients with the highest values in groups 2 and 3. Redo soft tissue inflammation occurred in all groups after treatment. Mean incidence was 25%. Two (10.5%) patients died in the 2 group and 1 (25%) patient in the 3 group.

CONCLUSION

The modern classification of sternomediastinitis does not fully characterize severity of disease in a particular patient. Simultaneous debridement with wound closure demonstrates acceptable mortality (within 10%). The highest mortality rate was observed in patients with diffuse lesions of the sternum. Less aggressive treatment approaches are possible for stable anterior chest wall.

摘要

目的

分析疾病不同阶段(埃尔·奥克利分类法)的骨组织损伤情况、每种临床情况的治疗方案以及每种治疗方法后的结果。

材料与方法

2022年10月至2023年9月期间,有45例心脏手术后出现伤口并发症的患者。38例(84.4%)患者接受了冠状动脉旁路移植术(CABG),7例(15.6%)患者接受了心脏瓣膜或主动脉手术。患者的平均年龄为68.1±10.3岁。男性35例(77.8%),女性10例(22.2%)。第1型在11例(24.5%)患者中发现,第2 - 3型在19例(42.2%)患者中发现,第4型在4例(8.8%)患者中发现,第5型在11例(24.5%)患者中发现。

结果

第1组7例(36.8%)患者、第2组14例(73.7%)患者、第3组4例(100%)患者和第4组2例(18.2%)患者出现全身炎症反应综合征。所有患者的C反应蛋白和降钙素原均升高,第2组和第3组的值最高。治疗后所有组均出现再次软组织炎症。平均发生率为25%。第2组有2例(10.5%)患者死亡,第3组有1例(25%)患者死亡。

结论

现代胸骨纵隔炎分类不能完全表征特定患者疾病的严重程度。同时进行清创和伤口闭合显示出可接受的死亡率(在10%以内)。胸骨弥漫性病变患者的死亡率最高。对于稳定的前胸壁,可以采用不太激进的治疗方法。

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