Department of Oto-Rhino-Laryngology, West China Hospital, Sichuan University, Chengdu, China.
Mental Health Center and Psychiatric Laboratory, West China Hospital of Sichuan University, Chengdu, China.
J Nerv Ment Dis. 2024 Aug 1;212(8):437-444. doi: 10.1097/NMD.0000000000001792. Epub 2024 Jul 15.
COVID-19 survivors complained of the experience of cognitive impairments, which also called "brain fog" even recovered. The study aimed to describe long-term cognitive change and determine psychosocial factors in COVID-19 survivors. A cross-sectional study was recruited 285 participants from February 2020 to April 2020 in 17 hospitals in Sichuan Province. Cognitive function, variables indicative of the virus infection itself, and psychosocial variables were collected by telephone interview. Univariate logistic regression and Lasso logistic regression models were used for variable selection which plugged into a multiple logistics model. Overall prevalence of moderate or severe cognitive impairment was 6.3%. Logistic regression showed that sex, religion, smoking status, occupation, self-perceived severity of illness, sleep quality, perceived mental distress after COVID-19, perceived discrimination from relatives and friends, and suffered abuse were associated with cognitive impairment. The long-term consequences of cognitive function are related to multiple domains, in which psychosocial factors should be taken into consideration.
COVID-19 幸存者抱怨出现认知障碍，甚至在康复后也被称为“脑雾”。本研究旨在描述 COVID-19 幸存者的长期认知变化，并确定其心理社会因素。2020 年 2 月至 4 月，在四川省的 17 家医院通过电话采访招募了 285 名参与者，进行横断面研究。通过电话采访收集认知功能、病毒感染本身的变量和心理社会变量。使用单变量逻辑回归和套索逻辑回归模型进行变量选择，然后将这些变量纳入多逻辑回归模型。中度或重度认知障碍的总体患病率为 6.3%。逻辑回归显示，性别、宗教、吸烟状况、职业、自我感知疾病严重程度、睡眠质量、COVID-19 后感知精神困扰、感知来自亲戚和朋友的歧视以及遭受虐待与认知障碍有关。认知功能的长期后果与多个领域相关，应考虑心理社会因素。
