经支气管冷冻消融术作为中央气道恶性肿瘤的局部治疗方法。
Transbronchial Cryoablation as Local Treatment for Central Airway Malignant Tumor.
机构信息
Department of Respiratory Medicine, Kurashiki Central Hospital, Okayama, Japan,
Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan.
出版信息
Respiration. 2024;103(9):587-592. doi: 10.1159/000540299. Epub 2024 Jul 22.
INTRODUCTION
Transbronchial cryoablation has been performed for peripheral but not central airway malignant tumor. We demonstrate transbronchial cryoablation in 2 patients with central airway lesions.
CASE PRESENTATION
Case 1 was an 86-year-old woman who developed intratracheal metastasis associated with postoperative recurrence of lung adenocarcinoma. The tumor was resected using a high-frequency electrosurgical snare and three transbronchial cryoablations. There was no tracheal recurrence in the 5 months after the third procedure. Case 2 was an 83-year-old man who developed intermediate bronchial metastasis associated with postoperative recurrence of lung squamous cell carcinoma. The tumor was resected using a high-frequency electrosurgical snare and one transbronchial cryoablation. There was no tumor recurrence in the bronchus intermedius for 12 months after treatment. In both cases, the only adverse event was minor bleeding.
CONCLUSION
Transbronchial cryoablation deserves consideration as local treatment for central airway malignant tumors.
介绍
经支气管冷冻消融术已应用于外周型气道而非中央型气道的恶性肿瘤。我们展示了 2 例中央气道病变患者经支气管冷冻消融术的治疗。
病例报告
病例 1 为 86 岁女性，术后复发性肺腺癌导致气管内转移。肿瘤使用高频电外科圈套器切除，并进行了 3 次经支气管冷冻消融术。第三次手术后 5 个月，气管无复发。病例 2 为 83 岁男性，术后复发性肺鳞癌导致中间支气管转移。肿瘤使用高频电外科圈套器切除，并进行了 1 次经支气管冷冻消融术。治疗后 12 个月，中间支气管未见肿瘤复发。在这两例中，唯一的不良事件是轻微出血。
结论
经支气管冷冻消融术值得考虑作为中央型气道恶性肿瘤的局部治疗方法。
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