Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA; Heidelberg Ion-Beam Therapy Center (HIT), Heidelberg, Germany; Division of Molecular and Translational Radiation Oncology, National Center for Tumor Diseases (NCT), Heidelberg University Hospital, Heidelberg, Germany; Clinical Cooperation Unit Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
UCLouvain, Molecular Imaging, Radiotherapy and Oncology (MIRO), Brussels, Belgium.
Radiother Oncol. 2024 Oct;199:110434. doi: 10.1016/j.radonc.2024.110434. Epub 2024 Jul 14.
There is a rising interest in developing and utilizing arc delivery techniques with charged particle beams, e.g., proton, carbon or other ions, for clinical implementation. In this work, perspectives from the European Society for Radiotherapy and Oncology (ESTRO) 2022 physics workshop on particle arc therapy are reported. This outlook provides an outline and prospective vision for the path forward to clinically deliverable proton, carbon, and other ion arc treatments. Through the collaboration among industry, academic, and clinical research and development, the scientific landscape and outlook for particle arc therapy are presented here to help our community understand the physics, radiobiology, and clinical principles. The work is presented in three main sections: (i) treatment planning, (ii) treatment delivery, and (iii) clinical outlook.
人们对于开发和利用带电粒子束（例如质子、碳或其他离子）的弧形输送技术越来越感兴趣，以便于临床应用。在这项工作中，报告了欧洲放射肿瘤学会（ESTRO）2022 年关于粒子弧形治疗的物理研讨会的观点。这种观点为临床可提供的质子、碳和其他离子弧形治疗提供了一个大纲和前瞻性的愿景。通过工业、学术和临床研究与开发的合作，呈现了粒子弧形治疗的科学前景，以帮助我们的社区了解物理、放射生物学和临床原则。这项工作主要分为三个部分：（i）治疗计划，（ii）治疗输送，和（iii）临床展望。
