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Assessment of Ki-67 and mitoses in pituitary neuroendocrine tumours-Consistency counts.

作者信息

Loughrey Paul Benjamin, Greene Christine, McCombe Kris D, Sidi Fatima Abdullahi, McQuaid Stephen, Cooke Stephen, Hunter Steven J, Herron Brian, Korbonits Márta, Craig Stephanie G, James Jacqueline A

机构信息

Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.

Regional Centre for Endocrinology and Diabetes, Belfast Health and Social Care Trust, Belfast, UK.

出版信息

Brain Pathol. 2025 Jan;35(1):e13285. doi: 10.1111/bpa.13285. Epub 2024 Jul 15.

Abstract

Pituitary neuroendocrine tumour Ki-67 proliferation index varies according to the number of tumour cells assessed. Consistent Ki-67 scoring approaches and re-evaluation of the recommended Ki-67 3% cut-off are required to clarify controversies in pituitary neuroendocrine tumour Ki-67 proliferation index assessment.

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