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口腔鳞状细胞癌中发现蝇蛆病:一例报告

Myiasis Encountered in Squamous Cell Carcinoma of the Oral Cavity: A Case Report.

作者信息

Khan Hassam Zaka, Shahid Syeda Aliza, Bakht Nausheen, Zaidi Syed Shahid Nafees

机构信息

Anatomy, Combined Military Hospital (CMH) Lahore Medical College and Institute of Dentistry, Lahore, PAK.

Pathology, Combined Military Hospital (CMH) Lahore Medical College and Institute of Dentistry, Lahore, PAK.

出版信息

Cureus. 2024 Jun 15;16(6):e62414. doi: 10.7759/cureus.62414. eCollection 2024 Jun.

DOI:10.7759/cureus.62414
PMID:39011201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11249050/
Abstract

Myiasis is a rare parasitic condition, caused by fly larvae infesting human tissues. Its consequences can be severe, as deafness, blindness, extensive tissue loss, and even death can occur due to the infestation. We present a case of myiasis in a 62-year-old Pakistani woman with advanced well-differentiated oral squamous cell carcinoma (OSCC) undergoing palliative chemotherapy. The patient presented with an extensive, necrotic lesion in the submental and submandibular region infested with live larvae. Management included mechanical removal over three sessions and ivermectin. Once all the larvae were eradicated, the patient was referred to the plastic surgery department for reconstruction. This case report highlights the importance of maintaining a high index of suspicion for myiasis in patients with OSCC, particularly those with extensive ulcerated lesions. Educating at-risk individuals and healthcare providers on myiasis and the importance of wound hygiene is crucial for reducing the burden of this preventable complication.

摘要

蝇蛆病是一种罕见的寄生虫病,由蝇幼虫寄生于人体组织引起。其后果可能很严重,因为感染可能导致耳聋、失明、广泛的组织损伤,甚至死亡。我们报告一例62岁患有晚期高分化口腔鳞状细胞癌(OSCC)并正在接受姑息化疗的巴基斯坦女性发生蝇蛆病的病例。患者颏下和下颌下区域出现广泛的坏死性病变,有活的幼虫寄生。治疗包括分三次进行机械清除以及使用伊维菌素。一旦所有幼虫被根除,患者被转诊至整形外科进行重建。本病例报告强调了对OSCC患者,尤其是那些有广泛溃疡病变的患者,保持对蝇蛆病高度怀疑指数的重要性。对高危个体和医护人员进行关于蝇蛆病及伤口卫生重要性的教育,对于减轻这种可预防并发症的负担至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff0/11249050/9e6762129c16/cureus-0016-00000062414-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff0/11249050/9e6762129c16/cureus-0016-00000062414-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff0/11249050/9e6762129c16/cureus-0016-00000062414-i01.jpg

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本文引用的文献

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Oral Myiasis in an Immunocompromised Adult Undergoing Chemotherapy: A Rare Case and Comprehensive Treatment Protocol.一名接受化疗的免疫功能低下成年人的口腔蝇蛆病:一例罕见病例及综合治疗方案
Cureus. 2023 Jul 27;15(7):e42555. doi: 10.7759/cureus.42555. eCollection 2023 Jul.
2
Oral myiasis: Analysis of cases reported in the English literature from 1990 to 2020.口腔蝇蛆病:1990 年至 2020 年英文文献报道病例分析。
Spec Care Dentist. 2021 Jan;41(1):20-31. doi: 10.1111/scd.12533. Epub 2020 Oct 30.
3
Treatment of facial myiasis in an elderly patient with oral squamous cell carcinoma: Case report.
老年口腔鳞状细胞癌患者面部蝇蛆病的治疗:病例报告
Int J Surg Case Rep. 2020;71:260-265. doi: 10.1016/j.ijscr.2020.05.015. Epub 2020 May 21.
4
Myiasis in patients with oral squamous cell carcinoma-a systematic review and protocol for management.口腔鳞状细胞癌患者的蝇蛆病——一项系统评价及管理方案
Oral Maxillofac Surg. 2019 Sep;23(3):265-269. doi: 10.1007/s10006-019-00757-2. Epub 2019 May 22.
5
Ivermectin: From theory to clinical application.伊维菌素:从理论到临床应用。
Int J Antimicrob Agents. 2019 Aug;54(2):134-142. doi: 10.1016/j.ijantimicag.2019.05.003. Epub 2019 May 7.
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Head and neck myiasis: a case series and review of the literature.头颈部蝇蛆病:病例系列及文献综述
Oral Surg Oral Med Oral Pathol Oral Radiol. 2017 Nov;124(5):e249-e256. doi: 10.1016/j.oooo.2017.06.120. Epub 2017 Jul 5.
7
Myiasis in patients with head and neck cancer: Seldom described but commonly seen.头颈部癌症患者的蝇蛆病:虽鲜有描述但常见。
Ear Nose Throat J. 2017 Jul;96(7):E19-E22. doi: 10.1177/014556131709600704.
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Myiasis Associated with Oral Squamous Cell Carcinoma--A Literature Review.与口腔鳞状细胞癌相关的蝇蛆病——文献综述
Asian Pac J Cancer Prev. 2015;16(12):4997-9. doi: 10.7314/apjcp.2015.16.12.4997.
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Dent Res J (Isfahan). 2015 Jan-Feb;12(1):100-5. doi: 10.4103/1735-3327.150343.
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