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上消化道伪装成贫血的巨大胃肠道间质瘤(GIST)

Huge Gastrointestinal Stromal Tumor (GIST) in Upper Gastrointestinal Masquerade Anaemia.

作者信息

Zahidin Muhammad Syamiel Irfan, Singh Jetinder, Mohammad Azmi Sumayyah, Azhar Azzahra, Md Hashim Mohd Nizam, Zakaria Andee Dzulkarnaen

机构信息

Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, MYS.

Department of Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, MYS.

出版信息

Cureus. 2024 Jun 14;16(6):e62409. doi: 10.7759/cureus.62409. eCollection 2024 Jun.

Abstract

Gastrointestinal stromal tumor (GIST) represents a rare neoplasm affecting the gastrointestinal (GI) tract and is classified as a common nonepithelial tumor within the GI tract. It originates from the interstitial cells of Cajal, and GIST typically manifests with symptoms such as abdominal pain, weight loss, and gastrointestinal bleeding. This case involves a 33-year-old male who presented with GI bleeding symptoms after eight months of treatment for anemia. Oesophagogastroduodenoscopy (OGDS) revealed a singular ulcerated mass measuring 4x4cm while a computed tomography (CT) scan identified a large fundal exophytic component extending from the gastroesophageal junction to the stomach. Subsequently, the patient underwent a laparotomy and proximal gastrectomy with Roux-en-Y reconstruction, which revealed a 12x10 cm tumor located at the fundus of the stomach. This report aims to underscore the potential for misdiagnosis in the initial presentation of GIST, emphasizing the importance of raising clinical awareness in such cases.

摘要

胃肠道间质瘤(GIST)是一种罕见的影响胃肠道(GI)的肿瘤,被归类为胃肠道常见的非上皮性肿瘤。它起源于 Cajal 间质细胞,GIST 通常表现为腹痛、体重减轻和胃肠道出血等症状。该病例涉及一名 33 岁男性,在接受贫血治疗八个月后出现胃肠道出血症状。食管胃十二指肠镜检查(OGDS)发现一个 4x4cm 的单发溃疡肿块,而计算机断层扫描(CT)显示一个从胃食管交界处延伸至胃的大的胃底外生性成分。随后,患者接受了剖腹手术和近端胃切除术并进行 Roux-en-Y 重建,术中发现一个位于胃底的 12x10 cm 肿瘤。本报告旨在强调 GIST 初始表现时误诊的可能性,强调在此类病例中提高临床认识的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c7c/11247141/95a127aa1a0d/cureus-0016-00000062409-i01.jpg

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