Department of BioBank, Kunshan Hospital Affiliated to Jiangsu University, Suzhou 215300, PR China.
Department of Clinical Laboratory, Jinxi People's Hospital of Kunshan, Suzhou, Jiangsu 215300, PR China.
Biomed Pharmacother. 2024 Aug;177:117100. doi: 10.1016/j.biopha.2024.117100. Epub 2024 Jul 15.
Gastric cancer (GC) is the fifth most prevalent type of cancer in the whole world. Cuproptosis is discovered as a programmed cell death pathway and connected to cells' growth and death, as well as tumorigenesis. The relationship between cuproptosis and GC is still elusive. Two aspects of this study will elaborate the relationship between cuproptosis and immunotherapy as well as biomarkers in GC. Notably, the herein review is intended to highlight what has been accomplished regarding the cuproptosis for the diagnosis, immunotherapy, and prognosis in GC. The aim of this study is to offer a potential directions and the strategies for future research regarding cuproptosis inside the GC.
胃癌（GC）是全球第五大常见癌症类型。铜死亡是一种新发现的程序性细胞死亡途径，与细胞的生长和死亡以及肿瘤发生有关。铜死亡与 GC 之间的关系仍不清楚。本研究的两个方面将详细阐述铜死亡与 GC 中的免疫治疗和生物标志物之间的关系。值得注意的是，本文旨在强调铜死亡在 GC 的诊断、免疫治疗和预后方面所取得的成果。本研究旨在为 GC 中的铜死亡提供未来研究的潜在方向和策略。
