University of Minnesota, Department of Biochemistry, Molecular Biology, and Biophysics, Minneapolis, MN, USA.
University of Minnesota, Department of Biochemistry, Molecular Biology, and Biophysics, Minneapolis, MN, USA.
Cell Rep Methods. 2024 Jul 15;4(7):100821. doi: 10.1016/j.crmeth.2024.100821.
Molecular tension sensors are central tools for mechanobiology studies but have limitations in interpretation. Reporting in Cell Reports Methods, Shoyer et al. discover that fluorescent protein photoswitching in concert with sensor extension may expand the use and interpretation of common force-sensing tools.
分子张力传感器是机械生物学研究的重要工具,但在解释方面存在局限性。在《细胞报告方法》杂志上发表的研究中,Shoyer 等人发现,荧光蛋白光开关与传感器延伸相结合,可能会扩大常见力感测工具的使用和解释。