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哌拉西林、头孢噻吩和头孢西丁预防腹腔内手术患者术后感染的前瞻性双盲比较。

A prospective double-blind comparison of piperacillin, cephalothin and cefoxitin in the prevention of postoperative infections in patients undergoing intra-abdominal operations.

作者信息

Baker R J, Donahue P E, Finegold S M, Johnson W C, Middleton J R, Monafo W W, Wilson S E

出版信息

Surg Gynecol Obstet. 1985 Nov;161(5):409-15.

PMID:3901357
Abstract

Piperacillin has been shown to be as safe and effective an agent as cephalothin and cefoxitin when used in patients undergoing elective intra-abdominal surgical procedures. Enterococcus species have been shown in other studies to be susceptible to piperacillin, perhaps making it the preferred antibiotic for prophylaxis in clinical settings when enteric flora will be encountered.

摘要

哌拉西林已被证明,在接受择期腹部外科手术的患者中使用时,它与头孢噻吩和头孢西丁一样安全有效。其他研究表明,肠球菌属对哌拉西林敏感,这或许使其成为在临床环境中预防会遇到肠道菌群时的首选抗生素。

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Re-emphasis of priorities in surgical antibiotic prophylaxis.
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