Division of Maxillofacial Diagnostic, Medical and Surgical Sciences, University College London, London, UK
Oral and Maxillofacial Unit, St Richard's Hospital, University Hospitals Sussex NHS Foundation Trust, Chichester, UK.
BMJ Case Rep. 2024 Jul 16;17(7):e258871. doi: 10.1136/bcr-2023-258871.
Leiomyoma is a benign tumour of smooth muscle origin. Leiomyoma arising in major salivary gland is under-reported. We report a case of a woman in her 40s with a submandibular gland tumour which represented a diagnostic challenge during preoperative assessment. The core needle biopsy of submandibular gland tumour revealed a spindle cell tumour suggestive of an undifferentiated tumour. As a malignancy could not be excluded, the submandibular gland tumour was removed en bloc with surrounding lymph nodes in level Ib of the neck. Leiomyoma may be included in the differential diagnosis of spindle cell salivary gland tumours, particularly when there are no signs of infiltration and preoperative investigations are inconclusive.
平滑肌瘤是一种良性的平滑肌来源肿瘤。发生在大唾液腺的平滑肌瘤报道较少。我们报告了一例 40 多岁女性的下颌下腺肿瘤，该肿瘤在术前评估期间具有诊断挑战性。下颌下腺肿瘤的芯针活检显示提示未分化肿瘤的梭形细胞肿瘤。由于不能排除恶性肿瘤，因此整块切除了下颌下腺肿瘤及其周围的颈内 Ib 水平淋巴结。当无浸润迹象且术前检查结果不确定时，平滑肌瘤可能被纳入梭形细胞唾液腺肿瘤的鉴别诊断中，特别是当无浸润迹象且术前检查结果不确定时。
