Ringelstein E B, Zeumer H, Poeck K
Stroke. 1985 Sep-Oct;16(5):848-55. doi: 10.1161/01.str.16.5.848.
The accuracy and the reliability of extracranial vertebral Doppler flow (continuous wave Doppler sonography) for the detection of intracranial vertebrobasilar lesions was studied prospectively in twenty-one patients with brainstem disturbances and/or coma. The Doppler findings were compared with cerebral angiography. Doppler sonography was highly reliable for both detection and exclusion of high grade intracranial vertebrobasilar lesions. The pathognomonic Doppler finding was an abrupt deceleration of the blood column during systole and stoppage or even reflux during diastole. The same blood flow alterations were found in two additional illustrative cases having therapeutically or brain-death induced blockages of the vertebral arteries. The pathophysiologic mechanisms of flow disturbances and the limitations of Doppler sonography in this area are discussed.
对21例患有脑干功能障碍和/或昏迷的患者进行了前瞻性研究，以评估颅外椎动脉多普勒血流（连续波多普勒超声检查）检测颅内椎基底动脉病变的准确性和可靠性。将多普勒检查结果与脑血管造影结果进行了比较。多普勒超声检查在检测和排除高级别颅内椎基底动脉病变方面具有高度可靠性。典型的多普勒表现为收缩期血柱突然减速，舒张期血流停止甚至反流。在另外两例因治疗或脑死亡导致椎动脉闭塞的典型病例中也发现了相同的血流改变。本文讨论了血流紊乱的病理生理机制以及多普勒超声检查在该领域的局限性。
