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非免疫功能低下年轻女性的下睑默克尔细胞癌:一例报告

Lower Eyelid Merkel Cell Carcinoma in a Non-Immunocompromised Young Female: A Case Report.

作者信息

Komatsu Yoshifumi, Kitaguchi Yoshiyuki, Kurashige Masako, Morimoto Takeshi, Nishida Kohji

机构信息

Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan.

Department of Pathology, Graduate School of Medicine, Osaka University, Suita, Japan.

出版信息

Case Rep Ophthalmol. 2024 May 17;15(1):437-442. doi: 10.1159/000536098. eCollection 2024 Jan-Dec.

Abstract

INTRODUCTION

Merkel cell carcinoma (MCC) is a rare neuroendocrine skin tumor associated with Merkel cell polyomavirus and ultraviolet light exposure. MCC typically affects older individuals, and it also influences young patients with immunosuppressive conditions. We report a case of lower eyelid MCC in a non-immunocompromised 37-year-old woman.

CASE PRESENTATION

A 37-year-old woman presenting with suspected MCC on her right lower eyelid was referred to our hospital for further resection. The patient underwent wide excision with clear margins followed by reconstruction and radiation therapy. The patient has shown no signs of recurrence after 5 months of follow-up.

CONCLUSION

MCC needs to be considered as a possible diagnosis when examining an eyelid tumor in a young patient.

摘要

引言

默克尔细胞癌(MCC)是一种罕见的神经内分泌性皮肤肿瘤,与默克尔细胞多瘤病毒及紫外线暴露有关。MCC通常影响老年人,也会影响有免疫抑制状况的年轻患者。我们报告一例37岁非免疫功能低下女性下眼睑MCC病例。

病例介绍

一名右眼下眼睑疑似MCC的37岁女性被转诊至我院进行进一步切除。患者接受了切缘清晰的广泛切除,随后进行了重建和放射治疗。随访5个月后,患者未出现复发迹象。

结论

在检查年轻患者的眼睑肿瘤时,需要考虑MCC作为可能的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3875/11250470/e65d17c9d7a8/cop-2024-0015-0001-536098_F01.jpg

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