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首例新冠疫苗接种后发生的暴发性化脓性肉芽肿病例。

The First Case of Eruptive Pyogenic Granuloma following COVID-19 Vaccination.

作者信息

Al-Zahawi Saman, Ghanadan Alireza, Saberi Fatema, Balighi Kamran, Razavi Zahra

机构信息

Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran.

Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran.

出版信息

Case Rep Dermatol. 2024 Jul 15;16(1):190-197. doi: 10.1159/000539849. eCollection 2024 Jan-Dec.

Abstract

INTRODUCTION

Pyogenic granuloma presents clinically as a rapidly growing, friable, red papule of skin or mucosa, commonly measuring less than 10 mm with frequent bleeding due to ulceration. Angioproliferative diseases including pyogenic granuloma and cherry angioma have been reported during COVID-19 infection or following COVID-19 vaccination.

CASE PRESENTATION

Here, we report a 52-year-old female patient who developed diffuse skin eruptions 3 weeks after the second dose of COVID-19 vaccination.

CONCLUSION

As per our knowledge, this is the first case of eruptive PG following COVID-19 vaccination. Oral propranolol and PDL laser therapy were administered after obtaining inconvenient results from electro-cautery, and there was a good response within 6 weeks of starting therapy, defined by the cessation of new lesion formation and a decrease in the size of large lesions.

摘要

引言

化脓性肉芽肿在临床上表现为皮肤或黏膜上迅速生长、质地脆、红色的丘疹,通常直径小于10毫米,因溃疡而频繁出血。包括化脓性肉芽肿和樱桃状血管瘤在内的血管增生性疾病在新冠病毒感染期间或新冠病毒疫苗接种后已有报道。

病例报告

在此,我们报告一名52岁女性患者,在接种第二剂新冠病毒疫苗3周后出现弥漫性皮肤疹。

结论

据我们所知,这是首例新冠病毒疫苗接种后爆发性化脓性肉芽肿病例。在电灼治疗效果不佳后,给予口服普萘洛尔和脉冲染料激光治疗,开始治疗后6周内有良好反应,表现为新病灶形成停止和大病灶尺寸减小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c341/11250667/8156633b858b/cde-2024-0016-0001-539849_F01.jpg

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