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卡塔尔患者对未使用药物的知识、态度和行为:一项横断面调查。

Patients' knowledge, attitude, and practices toward unused medications in Qatar: A cross-sectional survey.

作者信息

Makki Mutaseim, Akmal Shafie Asrul, Awaisu Ahmed, Hussain Rabia, Al Hail Moza, ElMotasim Walid Mohammed, Mohamed Ali Taha Mohamed Yousif, Abdoun Einas, Al-Khuzaei Noriya Mohd J, Salama Gamila, Pallivalapila Abdulrouf, El Kassem Wessam, Thomas Binny

机构信息

Pharmacy and Drug Control Department, Ministry of Public Health-Qatar, P.O Box 1919, Qatar.

School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, 11800, Malaysia.

出版信息

Heliyon. 2024 May 25;10(12):e31931. doi: 10.1016/j.heliyon.2024.e31931. eCollection 2024 Jun 30.

Abstract

BACKGROUND

Global evidence has linked unused medications and their inappropriate disposal to adverse health, economic, environmental, and ethical impacts. However, such evidence is scarce in Qatar. This study explored patients' knowledge and attitude toward unused medications and their practices toward medication supply and disposal (KAP) in Qatar.Materials and methods.

STUDY DESIGN

A cross-sectional survey using a pretested questionnaire was performed between February 2020 and October 2020. Descriptive statistics, Man Whitney U, and Kruskal-Wallis Rank-Sum tests were applied. The Chi square test assessed the association between socio-demographic characteristics and KAP scores. Characteristics that were found significantly associated with KAP (i.e., p-values <0.05) were further included as predictor variables in the multiple linear regression model.

RESULTS

All items pertaining to patients' knowledge were found to be good (mean score 3), except for "awareness of unwanted medication return policy" (mean score 3), i.e., the lowest level of patient agreement (31 %) (median (M) = 3, Interquartile Range (IQR) = 3). Their attitude was generally good (mean score 3). Conversely, their practice toward medication supply was poor (mean score 3). Possible future use was the most reported reason (79 %) for keeping medications at home, and home trash was the most widely disposing place of unused ones (76 %). Knowledge was significantly higher among non-laborers and other occupations than among patients with no work (p < 0.001) and (p = 0.005), respectively. The attitude was significantly lower among patients with healthcare providers (HCPs) in their household than among those without (p = 0.001). Practices were also significantly lower among those aged 40-49 years and those with HCPs in their household than those aged 18-29 years (p = 0.012) and those without HCPs, (p < 0.001), respectively.

CONCLUSIONS

Overall, patients' knowledge and attitude toward unused medications seem good, while their practices toward medication supply and disposal are bad. To mitigate the health, economic, and environmental impacts of unused medications, interventions including rationalizing drug supply, use, disposal, prescribing, manufacturing, and promotion are recommended.

摘要

背景

全球证据表明,未使用的药物及其不当处置会对健康、经济、环境和伦理产生不利影响。然而,卡塔尔缺乏此类证据。本研究探讨了卡塔尔患者对未使用药物的知识和态度,以及他们在药物供应和处置方面的行为(知识、态度和行为)。材料与方法。

研究设计

于2020年2月至2020年10月期间采用预先测试的问卷进行横断面调查。应用描述性统计、曼-惠特尼U检验和克鲁斯卡尔-沃利斯秩和检验。卡方检验评估社会人口学特征与知识、态度和行为得分之间的关联。在多元线性回归模型中,将与知识、态度和行为显著相关的特征(即p值<0.05)进一步作为预测变量纳入。

结果

发现所有与患者知识相关的项目表现良好(平均得分>3),但“对不需要的药物回收政策的知晓度”(平均得分=3)除外,即患者同意程度最低(31%)(中位数(M)=3,四分位间距(IQR)=3)。他们的态度总体良好(平均得分>3)。相反,他们在药物供应方面的行为较差(平均得分=3)。可能的未来使用是在家中保留药物的最常见原因(79%),而家庭垃圾是未使用药物最广泛的处置地点(76%)。非劳动者和其他职业的患者的知识水平分别显著高于无工作的患者(p<0.001)和(p=0.005)。家中有医疗保健提供者(HCP)的患者的态度显著低于没有HCP的患者(p=0.001)。40-49岁的患者以及家中有HCP的患者在药物供应和处置方面的行为也分别显著低于18-29岁的患者(p=0.012)和没有HCP的患者(p<0.001)。

结论

总体而言,患者对未使用药物的知识和态度似乎良好,而他们在药物供应和处置方面的行为较差。为减轻未使用药物对健康、经济和环境的影响,建议采取包括合理用药供应、使用、处置、处方、生产和推广等干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d172/11250874/ee4faca6922d/gr1.jpg

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