Mersin State Hospital, Clinic of Ophthalmology, Mersin.
Department of Ophthalmology, Niğde Ömer Halisdemir University, Niğde.
J Craniofac Surg. 2024 Oct 1;35(7):e658-e660. doi: 10.1097/SCS.0000000000010472. Epub 2024 Jul 17.
Upper eyelid blepharoplasty is one of the most common surgeries performed worldwide. However, an important problem after surgery is scar formation. The authors aimed to compare the efficacy of extractum cepae and silicone-based gels on postoperative scar appearance in patients undergoing upper eyelid blepharoplasty.
After suture removal, patients were divided into 3 groups: group 1 [n=82, extractum cepae, sodium heparin, and allantoin mixture, Contractubex Gel (Merz Pharmaceuticals, Frankfurt, Germany)], group 2 [n=81, silicone-based gel (Dermatix Ultra Silicone Gel, Menarini, Singapore)], and group 3 (n=77, no additional treatment). Patients used the topical gels twice daily. All evaluations were performed on color photographs by 2 physicians during the postoperative first and third months.
The mean visual analog scale scores were significantly higher in all 3 groups in the postoperative first month (4.39±2.03, 4.41±2.57, and 4.33±2.46, respectively) compared with the postoperative third month (2.22±1.24, 2.15±1.38, and 2.29±1.47, respectively) ( P =0.014, 0.037, and 0.026, respectively). The "Is the scar more stiff" score was higher in the postoperative first month compared with the third month.
In conclusion, blepharoplasty scars improved up to the postoperative third month, but the topical gels used did not significantly improve the cosmetic appearance of blepharoplasty scars compared with the control group.
上眼睑成形术是全球最常见的手术之一。然而,手术后一个重要的问题是瘢痕形成。作者旨在比较提取 Cepae 和硅基凝胶对接受上眼睑成形术患者术后瘢痕外观的疗效。
缝线拆除后,患者分为 3 组:第 1 组[n=82, Cepae 提取物、肝素钠和尿囊素混合物,Contractubex Gel(Merz Pharmaceuticals,法兰克福,德国)]、第 2 组[n=81,硅基凝胶(Dermatix Ultra Silicone Gel,Menarini,新加坡)]和第 3 组(n=77,无额外治疗)。患者每天使用外用凝胶 2 次。所有评估均由 2 名医生在术后第 1 个月和第 3 个月通过彩色照片进行。
与术后第 3 个月相比(分别为 2.22±1.24、2.15±1.38 和 2.29±1.47),所有 3 组在术后第 1 个月的平均视觉模拟量表评分均明显更高(分别为 4.39±2.03、4.41±2.57 和 4.33±2.46)(P=0.014、0.037 和 0.026)。与术后第 3 个月相比,“瘢痕是否更僵硬”评分在术后第 1 个月更高。
总之,眼睑成形术瘢痕在术后第 3 个月有所改善,但与对照组相比,外用凝胶并未显著改善眼睑成形术瘢痕的美容外观。