Department of Mechanical and Industrial Engineering, Qatar University, Doha, Qatar.
Biomedical Research Center, Qatar University, Doha, Qatar.
J Biomater Sci Polym Ed. 2024 Oct;35(15):2402-2445. doi: 10.1080/09205063.2024.2380570. Epub 2024 Jul 17.
Protein-based wound dressings have garnered increasing interest in recent years owing to their distinct physical, chemical, and biological characteristics. The intricate molecular composition of proteins gives rise to unique characteristics, such as exceptional biocompatibility, biodegradability, and responsiveness, which contribute to the promotion of wound healing. Wound healing is an intricate and ongoing process influenced by multiple causes, and it consists of four distinct phases. Various treatments have been developed to repair different types of skin wounds, thanks to advancements in medical technology and the recognition of the diverse nature of wounds. This review has literature reviewed within the last 3-5 years-the recent progress and development of protein in wound dressings and the fundamental properties of an ideal wound dressing. Herein, the recent strides in protein-based state-of-the-art wound dressing emphasize the significant challenges and summarize future perspectives for wound healing applications.
近年来，由于其独特的物理、化学和生物学特性，基于蛋白质的伤口敷料引起了越来越多的关注。蛋白质复杂的分子组成赋予了其独特的特性，如卓越的生物相容性、可生物降解性和响应性，这有助于促进伤口愈合。伤口愈合是一个复杂且持续的过程，受到多种因素的影响，它由四个不同的阶段组成。由于医疗技术的进步和对伤口多样性的认识，已经开发出各种治疗方法来修复不同类型的皮肤伤口。本文对过去 3-5 年内的文献进行了综述，介绍了蛋白质在伤口敷料中的最新进展和发展以及理想伤口敷料的基本特性。本文强调了基于蛋白质的最先进伤口敷料的最新进展所面临的重大挑战，并总结了未来在伤口愈合应用方面的展望。
