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先天性膈疝的产前诊断和干预考虑。

Prenatal diagnostic and intervention considerations in congenital diaphragmatic hernia.

机构信息

Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, McGovern Medical School at the University of Texas Health Science Center, Houston, TX, United States.

Department of Obstetrics and Gynecology, Division of Fetal Intervention, McGovern Medical School at the University of Texas Health Science Center, Houston, TX, United States.

出版信息

Semin Pediatr Surg. 2024 Aug;33(4):151436. doi: 10.1016/j.sempedsurg.2024.151436. Epub 2024 Jul 2.

Abstract

Congenital diaphragmatic hernia (CDH) is a life-threatening birth defect with significant morbidity and mortality. The prenatal management of a pregnancy with a fetus affected with CDH is complex and requires a multi-disciplinary team approach. An improved understanding of prenatal diagnosis and management is essential to developing strategies to optimize outcomes for these patients. In this review, we explore the current knowledge on diagnosis, severity stratification, prognostic prediction, and indications for fetal intervention in the fetus with CDH.

摘要

先天性膈疝(CDH)是一种危及生命的出生缺陷,具有显著的发病率和死亡率。患有 CDH 的胎儿的产前管理复杂,需要多学科团队方法。深入了解产前诊断和管理对于制定策略以优化这些患者的结局至关重要。在这篇综述中,我们探讨了目前关于 CDH 胎儿的诊断、严重程度分层、预后预测以及胎儿干预指征的知识。

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