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出生体重与胸腔镜手术在食管闭锁和气管食管瘘患者中的应用:一项回顾性队列研究。

Birth weight and thoracoscopic approach for patients with esophageal atresia and tracheoesophageal fistula-a retrospective cohort study.

机构信息

Department of Pediatric Surgery and Urology, Wroclaw Medical University, Borowska 213, 50-556, Wroclaw, Poland.

出版信息

Surg Endosc. 2024 Sep;38(9):5076-5085. doi: 10.1007/s00464-024-11063-8. Epub 2024 Jul 17.

Abstract

BACKGROUND

This study aimed to analyze the results, feasibility and safety of the thoracoscopic approach for patients with esophageal atresia with tracheoesophageal fistula (EA/TEF) depending on the patient's birth weight.

METHODS

The study involved only type C and D EA/TEF. Among the analyzed parameters were the patients' characteristics, surgical treatment and post-operative complications: early mortality, anastomosis leakage, anastomosis strictures, chylothorax, TEF recurrence, and the need for fundoplication or gastrostomy.

RESULTS

145 consecutive newborns underwent thoracoscopic EA with TEF repair. They were divided into three groups-A (N = 12 with a birth weight < 1500 g), B (N = 23 with a birth weight ≥ 1500 g but < 2000 g), and C-control group (N = 110 with a birth weight ≥ 2000 g). Primary one-stage anastomosis was performed in 11/12 (91.7%) patients-group A, 19/23 (82.6%)-group B and 110 (100%)-group C. Early mortality was 3/12 (25%)-group A, 2/23 (8.7%)-group B, and 2/110 (1.8%)-group C and was not directly related to the surgical repair. There were no significant differences in operative time and the following complications: anastomotic leakage, recurrent TEF, esophageal strictures, and chylothorax. There were no conversions to an open surgery. Fundoplication was required in 0%-group A, 4/21 (19.0%)-group B, and 2/108 (1.9%)-group C survivors. Gastrostomy was performed in 1/9 (11.1%)-group A, 3/21 (14.3%)-group B and 0%-group C.

CONCLUSION

In an experienced surgeon's hands, even in the smallest newborns, the thoracoscopic approach may be safe, feasible, and worthy of consideration. Birth weight seems to be not a direct contraindication to the thoracoscopic approach.

摘要

背景

本研究旨在根据患者的出生体重分析胸腔镜治疗食管闭锁伴气管食管瘘(EA/TEF)患者的结果、可行性和安全性。

方法

本研究仅涉及 C 型和 D 型 EA/TEF。分析的参数包括患者特征、手术治疗和术后并发症:早期死亡率、吻合口漏、吻合口狭窄、乳糜胸、TEF 复发以及是否需要胃底折叠术或胃造口术。

结果

145 例连续新生儿行胸腔镜 EA 伴 TEF 修复。他们分为三组:A 组(N=12,出生体重<1500g)、B 组(N=23,出生体重≥1500g 但<2000g)和 C 对照组(N=110,出生体重≥2000g)。A 组 12 例(91.7%)患者行一期吻合,B 组 19 例(82.6%),C 对照组 110 例(100%)。A 组早期死亡率为 3/12(25%),B 组为 2/23(8.7%),C 对照组为 2/110(1.8%),与手术修复无直接关系。手术时间和以下并发症无显著差异:吻合口漏、TEF 复发、食管狭窄和乳糜胸。无转为开放性手术。A 组 0%(0/9)需要行胃底折叠术,B 组 19.0%(4/21)需要行胃底折叠术,C 对照组 1.9%(2/108)需要行胃底折叠术。A 组 11.1%(1/9)、B 组 14.3%(3/21)需要行胃造口术,C 对照组不需要行胃造口术。

结论

在经验丰富的外科医生手中,即使是最小的新生儿,胸腔镜方法也可能是安全、可行的,值得考虑。出生体重似乎不是胸腔镜方法的直接禁忌症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/11362424/7457eb0a2480/464_2024_11063_Fig1_HTML.jpg

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