Egorov T L, Kormer A Ia, Zimin N K, Vasilenko V T, Tsyganov L P
Kardiologiia. 1979 Nov;19(11):72-6.
The possibility of maintenance of circulation and subsequent restoration of the function of the heart in the organism of the donor, after 10-minute arrest of circulation, for transplantation of the heart was investigated. Study of the hemodynamic, biochemical, metabolic, and structural changes in the myocardium after 2-hour mechanical massage without and with pharmacological protection of the myocardium (glucose--insulin--potassium, hydrocortisone, dipyridamole), without and with restoration of cardiac activity in the organism of the donor and the recipient after transplantation of the second heart by the method suggested by Moory et al. in artificially created left ventricular insufficiency showed that direct mechanical massage of the heart may be used for its short-term preservation in the donor organism.
研究了在供体机体循环停止10分钟后,为进行心脏移植而维持循环以及随后恢复心脏功能的可能性。通过莫里等人提出的方法,在人工造成左心室功能不全的情况下,对在未进行心肌药理保护(葡萄糖 - 胰岛素 - 钾、氢化可的松、双嘧达莫)和进行心肌药理保护的情况下,对心脏进行2小时机械按摩后,以及在供体和受体机体移植第二颗心脏后心脏活动恢复和未恢复的情况下,对心肌的血流动力学、生化、代谢和结构变化进行了研究。结果表明,心脏直接机械按摩可用于在供体机体中对心脏进行短期保存。