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巨大喉肉芽肿导致的致命性窒息

Fatal asphyxia due to large laryngeal granuloma.

作者信息

Kumar Ajay, Rautji Ravi, Mridha Asit Ranjan, Behera Chittaranjan

机构信息

All India Institute of Medical Sciences, Department of Forensic Medicine & Toxicology, New Delhi, Delhi, India.

Bharati Vidyapeeth Medical College, Department of Forensic Medicine & Toxicology, Pune, India.

出版信息

Autops Case Rep. 2024 Jun 14;14:e2024496. doi: 10.4322/acr.2024.496. eCollection 2024.

Abstract

Laryngeal granuloma, vocal process granuloma, or post-intubation granuloma are benign, inflammatory lesions of the arytenoid cartilage vocal process. The etiology of laryngeal granulomas is multifactorial, such as chronic irritation due to endotracheal intubation, vocal cord injury or trauma, and gastroesophageal reflux disease. They can arise postoperatively after mucosal injury due to orotracheal intubation. Clinical manifestations include voice change and dyspnea, which may start one to four months after extubation and may rarely lead to asphyxia. We presented a case of death due to glottic granuloma occurring after a surgical procedure to remove a laryngeal polyp attributed to previous laryngeal injuries by multiple intubations.

摘要

喉肉芽肿、声带突肉芽肿或插管后肉芽肿是杓状软骨声带突的良性炎性病变。喉肉芽肿的病因是多因素的,如气管插管引起的慢性刺激、声带损伤或创伤以及胃食管反流病。它们可在经口气管插管导致黏膜损伤后术后发生。临床表现包括声音改变和呼吸困难,可能在拔管后1至4个月开始,很少会导致窒息。我们报告了一例因手术切除喉部息肉后发生声门肉芽肿导致死亡的病例,该喉部息肉归因于之前多次插管造成的喉部损伤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a999/11253911/76bf11fa3422/autopsy-14-e2024496-g01.jpg

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