Pathology, Forensic Science SA, SA, Adelaide, Australia.
School of Biomedicine, The University of Adelaide, Frome Road, Adelaide, South Australia, 5005, Australia.
Forensic Sci Med Pathol. 2022 Dec;18(4):554-556. doi: 10.1007/s12024-022-00530-0. Epub 2022 Sep 22.
An 86-year-old woman with Alzheimer disease collapsed in her nursing home and was not able to be resuscitated. At autopsy, the major findings were in the larynx where a pedunculated oncocytic cystadenoma had occluded the glottis. Oncocytic cysts or cystadenomas of the larynx are rare histologically benign lesions that account for only 0.1-1% of laryngeal lesions. While the usual presentation is of a sensation of a mass in the throat, hoarseness, or stridor, very occasionally, there may be acute airway compromise and sudden death. Oncocytic cystadenoma should, therefore, be included in the differential diagnosis of potentially lethal obstructive laryngeal lesions.
一位 86 岁患有阿尔茨海默病的女性在养老院中晕倒,且未能复苏。尸检时,喉部的主要发现是一个带蒂的嗜酸细胞瘤囊腺瘤已阻塞声门。喉部嗜酸细胞瘤性囊肿或囊腺瘤是罕见的组织学良性病变,仅占喉部病变的 0.1-1%。尽管常见的表现为喉部有异物感、声音嘶哑或喘鸣,但非常罕见的情况下,可能会出现急性气道阻塞和突然死亡。因此,嗜酸细胞瘤性囊腺瘤应包括在可能导致致命性阻塞性喉部病变的鉴别诊断中。