Vance R P, Geisinger K R
Cancer. 1985 Nov 1;56(9):2321-5. doi: 10.1002/1097-0142(19851101)56:9<2321::aid-cncr2820560931>3.0.co;2-q.
The authors report a case of pure nongestational choriocarcinoma of the ovary (NGCO) in a prepubertal female patient and emphasize the electron microscopic and immunohistochemical findings. Pure NGCO accounts for 0.6% or less of all ovarian neoplasms. Distinction from gestational choriocarcinoma of the ovary (GCO) is important because of the worse prognosis of NGCO. No distinctive ultrastructural or immunohistochemical differences were found between NGCO and GCO. Cytogenetic studies may be indicated in future cases to investigate potential reasons for the difference in prognosis.
作者报告了一例青春期前女性患者的纯非妊娠性卵巢绒毛膜癌（NGCO），并强调了电子显微镜和免疫组织化学检查结果。纯NGCO占所有卵巢肿瘤的0.6%或更少。由于NGCO预后较差，因此将其与妊娠性卵巢绒毛膜癌（GCO）区分开来很重要。未发现NGCO和GCO在超微结构或免疫组织化学上有明显差异。未来的病例可能需要进行细胞遗传学研究，以探究预后差异的潜在原因。
