Fischer M, Galanski M, Winterberg B, Vetter H
Cardiology. 1985;72 Suppl 1:143-6. doi: 10.1159/000173961.
Localization procedures are required in catecholamine-producing tumors after clinical and biochemical confirmation. Computed tomography, ultrasound and/or 131I-metaiodobenzylguanidine (131I-MIBG) scintigraphy was performed in patients with pheochromocytoma, neuroblastoma and metastases of carcinoid tumors. Whereas computed tomography and ultrasound reflect morphological abnormalities, adrenomedullary scintigraphy depends on hormonal activity and other factors. 131I-MIBG scintigraphy has the advantage of detecting extraadrenal, multilocular and malignant pheochromocytomas. Especially small lesions and tumor tissue in bone marrow in children with neuroblastoma can be visualized more easily.
在临床和生化确诊后，对于产生儿茶酚胺的肿瘤需要进行定位检查。对患有嗜铬细胞瘤、神经母细胞瘤和类癌转移瘤的患者进行了计算机断层扫描、超声检查和/或131I-间碘苄胍（131I-MIBG）闪烁扫描。计算机断层扫描和超声检查反映形态学异常，而肾上腺髓质闪烁扫描则取决于激素活性和其他因素。131I-MIBG闪烁扫描的优势在于能够检测肾上腺外、多房性和恶性嗜铬细胞瘤。特别是神经母细胞瘤患儿骨髓中的小病灶和肿瘤组织更容易被显示出来。
