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改良的混合Glubran支撑单导丝技术用于血管内动脉瘤修复术中穿刺口闭合的可行性

Feasibility of a modified hybrid glubran-supported single-proglide technique for access closure during endovascular aneurysm repair.

作者信息

Xu Chen, Xu Guo-Xiong, Chen Lei, Zhang Zhi-Xuan, Jin Yi-Qi

机构信息

Department of Vascular Surgery, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China.

出版信息

Front Cardiovasc Med. 2024 Jul 4;11:1426961. doi: 10.3389/fcvm.2024.1426961. eCollection 2024.

Abstract

OBJECTIVE

This study aimed to evaluate the feasibility of a hybrid Glubran-supported single-Proglide technique for large bore femoral access closure during percutaneous access endovascular aneurysm repair (EVAR).

METHODS

A retrospective cohort study was performed for all percutaneous EVARs at our center from January 2023 to June 2023. All patients received the hybrid Glubran-supported single-Proglide technique involving a mixture of surgical glue and Lipiodol injection after single suture placement for femoral access closure. Technical success was defined as achieving complete hemostasis without a bailout strategy. Vascular complications and bleeding were defined by Valve Academic Research Consortium-3 (VARC-3) criteria. Vascular access changes and 30-day mortality were recorded.

RESULTS

The technique success rate for the entire study population was 100% (55 femoral access in 37 patients; median age: 72; 78% males). The mean sheath size was 20.4 ± 2.3F. The mean manual compression time was 3.5 ± 1.4 min, the mean hemostasis time was 9.0 ± 2.5 min, and the mean procedural time was 103.9 ± 34.7 min. One patient (1.6%) developed an access site infection and recovered conservatively. No VARC-3 vascular complications and access changes were observed. No 30-day mortality happened.

CONCLUSIONS

The hybrid Glubran-supported single-Proglide technique is feasible for large bore access closure during EVAR and may be a viable alternative; however, larger prospective studies are required to confirm its efficacy.

摘要

目的

本研究旨在评估在经皮入路血管内动脉瘤修复术(EVAR)期间,采用混合Glubran支撑单Proglide技术闭合大口径股动脉穿刺点的可行性。

方法

对2023年1月至2023年6月在本中心进行的所有经皮EVAR手术进行回顾性队列研究。所有患者在单缝合法闭合股动脉穿刺点后,采用混合Glubran支撑单Proglide技术,包括注射手术胶水和碘油混合物。技术成功定义为无需补救策略即可实现完全止血。血管并发症和出血按照瓣膜学术研究联盟-3(VARC-3)标准进行定义。记录血管穿刺点变化和30天死亡率。

结果

整个研究人群的技术成功率为100%(37例患者中的55个股动脉穿刺点;中位年龄:72岁;78%为男性)。平均鞘管尺寸为20.4±2.3F。平均手动压迫时间为3.5±1.4分钟,平均止血时间为9.0±2.5分钟,平均手术时间为103.9±34.7分钟。1例患者(1.6%)发生穿刺点感染,经保守治疗后康复。未观察到VARC-3定义的血管并发症和穿刺点变化。未发生30天死亡率。

结论

混合Glubran支撑单Proglide技术在EVAR期间闭合大口径穿刺点是可行的,可能是一种可行的替代方法;然而,需要更大规模的前瞻性研究来证实其疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c0/11254816/85b680883789/fcvm-11-1426961-g001.jpg

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