Department of Nephrology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi India.
Department of Endocrinology, Bharti Hospital, Karnal, India.
J Pak Med Assoc. 2024 Jul;74(7):1374-1375. doi: 10.47391/JPMA.24-52.
This review delves into relatively less discussed role of alkaline phosphatase (ALP) as an accessible alternative to intact parathyroid hormone (iPTH) in the context of bone health assessment, particularly focussing on its potential boon for underprivileged individuals with chronic kidney disease (CKD) in South Asia. The financial constraints faced by this demographic often hinder regular monitoring of iPTH levels. ALP emerges as a promising surrogate, offering a cost-effective and practical solution for bone health evaluation in resource-constrained settings.
这篇综述深入探讨了碱性磷酸酶（ALP）作为骨健康评估中替代完整甲状旁腺激素（iPTH）的一个较不被讨论的角色，特别是关注其在南亚慢性肾脏病（CKD）弱势群体中的潜在益处。该人群面临的经济限制常常阻碍了对 iPTH 水平的定期监测。ALP 作为一种很有前途的替代物，为资源有限的环境中的骨健康评估提供了一种经济有效且实用的解决方案。
