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发展中国家一家三级医院的颅骨成形术结果。

Cranioplasty Outcomes from a Tertiary Hospital in a Developing Country.

机构信息

Department of Neurosurgery, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.

出版信息

Ann Afr Med. 2024 Apr 1;23(2):176-181. doi: 10.4103/aam.aam_53_23. Epub 2024 May 1.

Abstract

BACKGROUND

Decompressive craniectomy (DC) is a surgical procedure to treat refractory increase in intracranial pressure. DC is frequently succeeded by cranioplasty (CP), a reconstructive procedure to protect the underlying brain and maintain cerebrospinal fluid flow dynamics. However, complications such as seizures, fluid collections, infections, and hydrocephalus can arise from CP. Our aim is to investigate these complications and their possible risk factors and to discuss whether early or late CP has any effect on the outcome.

MATERIALS AND METHODS

A single-center retrospective cohort study was performed, including patients who underwent CP after DC between January 2014 and January 2022. Relevant information was collected such as demographics, type of brain injury, materials used in CP, timing between DC and CP, and postoperative complications. Ultimately, 63 patients were included in our study. We also compared the complication rate between patients who underwent late CP after DC (>90 days) against patients who underwent early CP (<90 days).

RESULTS

Most patients were male (78%). The sample median age was 29 years, with pediatric patients, accounting for 36% of the samples. Overall complication rate was 57% and they were seizure/epilepsy in 50% of the patients, fluid collection (28%), infections (25%), posttraumatic hydrocephalus (17%), and bone defect/resorption (3%). Twenty-two percent of patients with complications required reoperation and underwent a second CP. The median (interquartile range) duration between the craniotomy and the CP was 56 (27-102) days, with an early (≤3 months) percentage of 68%. We found no significant difference between early (≤3 months) and late (>3 months) CP regarding complication rates.

CONCLUSION

Despite CP being a simple procedure, it has a considerable rate of complications. Therefore, it is important that surgeons possess adequate knowledge about such complications to navigate these challenges more effectively.

摘要

背景

去骨瓣减压术(DC)是治疗颅内压升高的一种手术方法。DC 后常行颅骨修补术(CP),这是一种重建手术,以保护脑内组织并维持脑脊液动力学。然而,CP 后可能会出现癫痫发作、积液、感染和脑积水等并发症。我们的目的是研究这些并发症及其可能的危险因素,并讨论 CP 是早期进行还是晚期进行对预后的影响。

材料和方法

进行了一项单中心回顾性队列研究,纳入了 2014 年 1 月至 2022 年 1 月期间行 DC 后行 CP 的患者。收集了相关信息,如人口统计学资料、脑损伤类型、CP 中使用的材料、DC 与 CP 之间的时间以及术后并发症。最终,我们纳入了 63 例患者。我们还比较了 DC 后行晚期 CP(>90 天)与行早期 CP(<90 天)的患者的并发症发生率。

结果

大多数患者为男性(78%)。样本的中位年龄为 29 岁,其中儿童患者占 36%。总体并发症发生率为 57%,其中 50%的患者出现癫痫发作/癫痫,28%的患者出现积液,25%的患者出现感染,17%的患者出现创伤后脑积水,3%的患者出现骨缺损/吸收。22%的并发症患者需要再次手术,并进行了第二次 CP。颅骨切开术与 CP 之间的中位(四分位间距)时间为 56(27-102)天,早期(≤3 个月)比例为 68%。我们发现早期(≤3 个月)和晚期(>3 个月)CP 的并发症发生率没有显著差异。

结论

尽管 CP 是一种简单的手术,但它有相当高的并发症发生率。因此,外科医生需要充分了解这些并发症,以便更有效地应对这些挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6a/11210725/c6d7e373f8dd/AAM-23-176-g001.jpg

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