经口机器人手术在原发性不明头颈部鳞状细胞癌的诊断和治疗中的应用：初步的单中心经验。
Transoral robotic surgery in the diagnosis and treatment of primary unknown head and neck squamous cell carcinoma: A preliminary single centre experience.
机构信息
Department of General Surgery, Beijing United Family Hospital and Clinics, Beijing, China.
Department of Head and Neck Surgery, Peking University Cancer Hospital and Institute, Beijing, China.
出版信息
Int J Med Robot. 2024 Jun;20(3):e2652. doi: 10.1002/rcs.2652.
BACKGROUND
Squamous cell carcinoma of unknown primary (CUP) in the head and neck is difficult to diagnose and treat. This report outlines 11 cases of CUP treated with transoral robotic surgery (TORS), aimed at investigating the diagnostic efficiency of primary tumour and radical resection effectiveness of TORS.
METHODS
11 cases of CUP among 68 oropharyngeal cancer patients treated by TORS were analysed retrospectively.
RESULTS
All the 11 cases received TORS with cervical lymph node dissection. Primary tumours were found in 8 cases (72.7%), 4 cases in the palatine tonsil and 4 cases in the base of the tongue. The average diameter of the primary tumour was 1.65 cm. All patients resumed eating by mouth within 24 h, no tracheotomy, no pharyngeal fistula and no postoperative death. The 3-year disease-free survival rate was 91%.
CONCLUSIONS
TORS can improve the diagnostic efficiency of primary tumour of CUP and achieve good oncology and functional results.
背景
头颈部不明原发灶鳞状细胞癌（CUP）的诊断和治疗较为困难。本研究报告了 11 例经口机器人手术（TORS）治疗的 CUP 病例，旨在探讨 TORS 对原发灶的诊断效率和根治性切除效果。
方法
回顾性分析了 68 例经 TORS 治疗的口咽癌患者中的 11 例 CUP 病例。
结果
11 例患者均行 TORS 联合颈部淋巴结清扫术。8 例（72.7%）患者发现原发灶，其中 4 例位于扁桃体，4 例位于舌根，原发灶平均直径为 1.65 cm。所有患者术后 24 h 内恢复经口进食，无气管切开、咽瘘和术后死亡。3 年无疾病生存率为 91%。
结论
TORS 可提高 CUP 原发灶的诊断效率，获得良好的肿瘤学和功能结果。
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