Crane J P, Beaver H A, Cheung S W
J Ultrasound Med. 1985 Oct;4(10):519-24. doi: 10.7863/jum.1985.4.10.519.
Although commonly encountered in spontaneous abortions, triploidy is rarely seen in fetuses surviving beyond mid-pregnancy. Mid-trimester sonographic findings in three triploid fetuses are described and compared with those reported in six prior cases. While sonographic characteristics are variable, common features include: 1) second trimester-onset fetal growth retardation with a reduced growth potential pattern of anthropometric growth, 2) body asymmetry with relative macrocephaly and an elevated head:abdominal circumference ratio, 3) hydrocephalus, 4) oligohydramnios, and 5) an abnormally large and/or hydropic placenta (in cases of paternal origin). Genetic amniocentesis and amniotic fluid chromosome studies should be performed when ultrasound findings suggestive of fetal triploidy are identified.
虽然三倍体在自然流产中很常见，但在妊娠中期后存活的胎儿中却很少见。本文描述了3例三倍体胎儿在孕中期的超声检查结果，并与之前报道的6例病例进行了比较。虽然超声特征各不相同，但常见特征包括：1）孕中期开始出现胎儿生长受限，人体测量生长的生长潜能模式降低；2）身体不对称，相对巨头畸形，头围与腹围比值升高；3）脑积水；4）羊水过少；5）胎盘异常增大和/或水肿（父源性病例）。当超声检查发现提示胎儿三倍体时，应进行遗传羊膜腔穿刺术和羊水染色体研究。
