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评估中胚层疗法产品的疗效：Ultra Exo Booster 和 Ultra S Line Plus 在头发生长方面的作用：一项离体研究。

Assessing the efficacy of mesotherapy products: Ultra Exo Booster, and Ultra S Line Plus in hair growth: An ex vivo study.

机构信息

Department of Medicine, College of Medicine, Seoul National University, Seoul, South Korea.

Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea.

出版信息

Skin Res Technol. 2024 Jul;30(7):e13780. doi: 10.1111/srt.13780.

DOI:10.1111/srt.13780
PMID:39031929
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11259544/
Abstract

In this study, scalp tissues from Korean adults between 20 and 80 without skin disease were used. Scalp tissues were processed, and hair follicles were isolated and cultured with different treatments (including Bioscalp, Ultra Exo Booster, and Ultra S Line Plus) from Ultra V company. Over 12 days, observations and measurements of hair follicle characteristics were recorded at intervals (Days 0, 3, 6, 9, and 12). The study assessed the impact of these substances on hair follicle growth and morphology. Bioscalp, combined with Ultra Exo Booster and Ultra S Line Plus, showed significant hair elongation in ex vivo. Preservation of hair bulb diameter was observed, indicating potential for sustained hair growth by exosome-based products. The hair growth cycle analysis suggested a lower transition to the catagen stage in test products from Ultra V compared to non-treated groups. The research findings indicated that the tested formulations, especially the combination of Bioscalp, Ultra Exo Booster, and Ultra S Line Plus, demonstrated significant effectiveness in promoting hair growth, maintaining the integrity of the hair bulb, and reducing the transition to the catagen stage. The study suggests promising alternative treatments for hair loss, illustrating results that were as good as those of the conventional testing product groups.

摘要

本研究使用了来自 20 至 80 岁无皮肤病的韩国成年人的头皮组织。头皮组织经过处理，毛囊被分离并使用 Ultra V 公司的不同处理方法（包括 Bioscalp、Ultra Exo Booster 和 Ultra S Line Plus）进行培养。在 12 天的时间里，每隔一段时间（第 0、3、6、9 和 12 天）记录毛囊特征的观察和测量结果。该研究评估了这些物质对毛囊生长和形态的影响。Bioscalp 与 Ultra Exo Booster 和 Ultra S Line Plus 联合使用，在体外显著促进了头发的伸长。观察到毛球直径的保持，表明基于外泌体的产品具有持续促进头发生长的潜力。头发生长周期分析表明，与未处理组相比，Ultra V 测试产品中转到退行期的阶段较低。研究结果表明，测试的配方，尤其是 Bioscalp、Ultra Exo Booster 和 Ultra S Line Plus 的组合，在促进头发生长、维持毛球完整性和减少退行期转变方面具有显著效果。该研究为脱发提供了有前景的替代治疗方法，结果与传统测试产品组一样好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3042/11259544/c214abba483e/SRT-30-e13780-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3042/11259544/d4860117a920/SRT-30-e13780-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3042/11259544/2fa4b17b74c3/SRT-30-e13780-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3042/11259544/b14822392d83/SRT-30-e13780-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3042/11259544/7d19336164b4/SRT-30-e13780-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3042/11259544/209ee336c014/SRT-30-e13780-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3042/11259544/8c32d83aa7d3/SRT-30-e13780-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3042/11259544/c214abba483e/SRT-30-e13780-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3042/11259544/d4860117a920/SRT-30-e13780-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3042/11259544/2fa4b17b74c3/SRT-30-e13780-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3042/11259544/b14822392d83/SRT-30-e13780-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3042/11259544/7d19336164b4/SRT-30-e13780-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3042/11259544/209ee336c014/SRT-30-e13780-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3042/11259544/8c32d83aa7d3/SRT-30-e13780-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3042/11259544/c214abba483e/SRT-30-e13780-g007.jpg

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