Centre for Cognition and Brain Disorders, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China.
Department of Physical Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Psychophysiology. 2024 Nov;61(11):e14655. doi: 10.1111/psyp.14655. Epub 2024 Jul 19.
Neural oscillations are electrophysiological indicators of synchronous neuronal activity in the brain. Recent work suggests aberrant patterns of neuronal activity in patients with poststroke aphasia. Yet, there is a lack of systematic explorations of neural oscillations in poststroke aphasia. Investigating changes in the dynamics of neuronal activity after stroke may be helpful to identify neural markers of aphasia and language recovery and increase the current understanding of successful language rehabilitation. This review summarizes research on neural oscillations in poststroke aphasia and evaluates their potential as biomarkers for specific linguistic processes. We searched the literature through PubMed, Web of Science, and EBSCO, and selected 31 studies that met the inclusion criteria. Our analyses focused on neural oscillation activity in each frequency band, brain connectivity, and therapy-induced changes during language recovery. Our review highlights potential neurophysiological markers; however, the literature remains confounded, casting doubt on the reliability of these findings. Future research must address these confounds to confirm the robustness of cross-study findings on neural oscillations in poststroke aphasia.
神经振荡是大脑中神经元同步活动的电生理指标。最近的研究表明,脑卒中后失语症患者的神经元活动模式异常。然而,对于脑卒中后失语症的神经振荡,缺乏系统的探索。研究脑卒中后神经元活动的动态变化,可能有助于确定失语症和语言恢复的神经标志物,并增加对成功语言康复的现有理解。本综述总结了脑卒中后失语症的神经振荡研究,并评估了它们作为特定语言过程生物标志物的潜力。我们通过 PubMed、Web of Science 和 EBSCO 进行文献检索,并选择了符合纳入标准的 31 项研究。我们的分析集中在每个频带的神经振荡活动、脑连接以及语言恢复过程中的治疗诱导变化。我们的综述强调了潜在的神经生理标志物;然而,文献仍然存在混淆,这些发现的可靠性值得怀疑。未来的研究必须解决这些混淆,以确认脑卒中后失语症的神经振荡的跨研究发现的稳健性。