Servicio de Cardiología, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain.
Servicio de Cardiología, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Rev Esp Cardiol (Engl Ed). 2024 Nov;77(11):926-935. doi: 10.1016/j.rec.2024.05.015. Epub 2024 Jul 18.
Our aim was to describe the characteristics and outcomes of heart transplants in Spain.
We analyzed trends in recipient and donor characteristics, recipient-donor interaction, surgical procedures, immunosuppression, and outcomes of patients included in the Spanish heart transplant registry from 2014 to 2023. Changes in survival were analyzed using the Kaplan-Meier method.
In 2023, 325 cardiac transplants were performed (4.5% more than in the previous year), with a total of 2987 procedures from 2014 to 2023. There was a trend toward performing more transplants in women (29.2%), with etiologies other than cardiomyopathy (32.6%), and with better pretransplant status (less hepatic [12.5%], renal [glomerular filtration rate, 81.5mL/min/1.73 m], and respiratory [8.7%] involvement). In 2023, the number of urgent transplants increased (44% of the total), especially those performed after circulatory support with extracorporeal membrane oxygenation (36% of total assistance), and transplants performed with donation after circulatory death (17.9%). Survival improved in the triennium from 2020 to 2022 compared with 2014 to 2016 (83.0% at 1 year from 2020-2022 vs 79.0% from 2014-2016).
The number of transplants performed in Spain showed an upward trend, with recipients with better clinical status and an increasing use of donation after circulatory death. Survival improved in the last triennium.
我们旨在描述西班牙心脏移植的特点和结果。
我们分析了 2014 年至 2023 年期间西班牙心脏移植登记处中受者和供者特征、受者-供者相互作用、手术程序、免疫抑制和患者结局的趋势。使用 Kaplan-Meier 方法分析生存变化。
2023 年进行了 325 例心脏移植(比前一年增加 4.5%),2014 年至 2023 年共有 2987 例手术。进行更多女性(29.2%)、非心肌病病因(32.6%)和更好的移植前状态(肝[12.5%]、肾[肾小球滤过率,81.5mL/min/1.73 m]和呼吸[8.7%]受累较少)移植的趋势。2023 年,紧急移植数量增加(占总数的 44%),特别是在体外膜氧合循环支持后进行的移植(占总辅助的 36%),以及使用死后循环捐献进行的移植(17.9%)。与 2014 年至 2016 年相比,2020 年至 2022 年的三年期间生存率提高(2020-2022 年的 1 年生存率为 83.0%,而 2014-2016 年为 79.0%)。
西班牙进行的移植数量呈上升趋势,受者临床状况较好,死后循环捐献的使用不断增加。最后三年的生存率提高了。