Harman E M
Med Clin North Am. 1985 Jul;69(4):705-14. doi: 10.1016/s0025-7125(16)31015-x.
The term "immunologic lung disease" comprises a broad spectrum of disease. I have covered a few entities in which recent studies have been particularly helpful in elucidating pathophysiology though not in uncovering the inciting cause. Common to all of these entities is the problem of finding appropriate methods of defining disease activity and response to treatment. As exemplified by the improved outlook for Goodpasture's syndrome with elucidation of its underlying immunopathology, it is likely that better understanding of the immunologic basis of sarcoid and interstitial disease may be helpful in planning more effective treatment strategies.
“免疫性肺病”这一术语涵盖了广泛的疾病。我已经介绍了一些疾病实体,在这些实体中,近期的研究对阐明病理生理学特别有帮助,尽管尚未揭示引发原因。所有这些疾病实体的共同问题是找到定义疾病活动和治疗反应的合适方法。正如随着对其潜在免疫病理学的阐明,Goodpasture综合征的预后得到改善所例证的那样,更好地理解结节病和间质性疾病的免疫基础可能有助于制定更有效的治疗策略。