Clin Nephrol. 2024 Oct;102(4):238-243. doi: 10.5414/CN111259.
Fibrillary glomerulonephritis (FGN) is a rare glomerular disease defined by the presence of microfibrils that deposit within the glomeruli. While initially thought to be idiopathic, FGN is now recognized to be associated with infection, malignancies, and autoimmune disorders. We describe a case of biopsy-proven FGN in a patient with seropositive rheumatoid arthritis (RA) and provide a review of the literature regarding the association of FGN with RA.
纤维状肾小球肾炎(FGN)是一种罕见的肾小球疾病,其特征是肾小球内存在微纤维沉积。虽然最初被认为是特发性的,但现在已经认识到 FGN 与感染、恶性肿瘤和自身免疫性疾病有关。我们描述了一例血清阳性类风湿关节炎(RA)患者的活检证实的 FGN,并回顾了有关 FGN 与 RA 相关性的文献。