Department of Animal, Poultry, and Fish Production, Faculty of Agriculture, Damietta University, Damietta, Egypt.
Department of Zoology, College of Science, King Saud university, Riyadh, Saudi Arabia.
J Anim Physiol Anim Nutr (Berl). 2024 Nov;108(6):1877-1889. doi: 10.1111/jpn.14027. Epub 2024 Jul 23.
The trail aimed to explore the effect of dietary supplementation of curcumin loaded olive oil nanoemulsion (CUR-OLNE) on growth performance, feed utilization, blood biochemical, redox status, and immune response of Litopenaeus vannamei shrimp, considering the economic efficiency of supplementation. A total of 280 healthy shrimps (3.42 ± 0.02 g) were randomly distributed into five equal groups and were fed diets containing 0 (CUR-OLNE0), 5(CUR-OLNE5), 10(CUR-OLNE10), 15(CUR-OLNE15) and 20 (CUR-OLNE20) mg CUR-OLNE/kg diet, respectively for 16 weeks. Among CUR-OLNE treated groups, CUR-OLNE20 showed the highest growth performance and feed utilization traits, including final body weight, specific growth rate, feed conversion ratio, and protein efficiency ratio. Notably, the photomicrographs provided further compelling evidence regarding the potential effect of CUR-OLNE supplementation on muscle structure and integrity. Compared to the control, the levels of blood protein significantly induced in CUR-OLNE15 and CUR-OLNE20 treated groups (p < 0.05). All CUR-OLNE -supplemented groups possessed lower activities of liver enzymes as well as the levels of urea and creatinine compared to the control (p < 0.05). The addition of 20 mg CUR-OLNE/kg diet decreased the concentrations of cortisol, glucose and triglycerides. The dietary treatment significantly improved the secretion of digestive enzymes, including amylase, lipase, and protease. The lowest levels of Malondialdehyde and the highest levels of total antioxidant capacity, super oxide dismutase, catalase, lysozyme and immunoglobulin M were detected in both of CUR-OLNE15, and CUR-OLNE20 treated groups compared to the control (p < 0.05). There were considerable significant effects of dietary supplementation of CUR-OLNE on economic efficiency. In conclusion, the application of nanocarriers for the delivery of dietary immune stimulants such as CUR-OLNE to Litopenaeus vannamei shrimp is a promising strategy for improving shrimp nutrition. The addition of 20 mg CUR-OLNE/kg to the diets of can be recommended as an affective intervention to improve growth performance, feed utilization, and health status of shrimp. Implementing this intervention can maximize the economic efficiency of shrimp farming while promoting sustainable practices in the industry.
本研究旨在探索膳食补充姜黄素负载橄榄油纳米乳液（CUR-OLNE）对凡纳滨对虾生长性能、饲料利用、血液生化、氧化还原状态和免疫反应的影响，同时考虑补充的经济性。将 280 只健康虾（3.42±0.02g）随机分为 5 组，每组等分为 5 组，分别投喂含 0（CUR-OLNE0）、5（CUR-OLNE5）、10（CUR-OLNE10）、15（CUR-OLNE15）和 20（CUR-OLNE20）mg CUR-OLNE/kg 饲料的日粮，共 16 周。在 CUR-OLNE 处理组中，CUR-OLNE20 表现出最高的生长性能和饲料利用特性，包括最终体重、特定生长率、饲料转化率和蛋白质效率比。值得注意的是，显微镜照片进一步提供了关于 CUR-OLNE 补充对肌肉结构和完整性的潜在影响的有力证据。与对照组相比，CUR-OLNE15 和 CUR-OLNE20 处理组的血液蛋白水平显著升高（p<0.05）。与对照组相比，所有添加 CUR-OLNE 的组的肝酶活性以及尿素和肌酐水平均降低（p<0.05）。添加 20mg CUR-OLNE/kg 日粮可降低皮质醇、葡萄糖和甘油三酯的浓度。日粮处理显著提高了淀粉酶、脂肪酶和蛋白酶等消化酶的分泌。与对照组相比，CUR-OLNE15 和 CUR-OLNE20 处理组的丙二醛含量最低，总抗氧化能力、超氧化物歧化酶、过氧化氢酶、溶菌酶和免疫球蛋白 M 含量最高（p<0.05）。膳食补充 CUR-OLNE 对经济效益有显著影响。总之，将纳米载体用于向凡纳滨对虾输送膳食免疫刺激物，如 CUR-OLNE，是提高虾类营养的一种很有前途的策略。在饲料中添加 20mg CUR-OLNE/kg 可以作为一种有效的干预措施，提高虾的生长性能、饲料利用率和健康状况。实施这一干预措施可以最大限度地提高虾类养殖的经济效益，同时促进该行业的可持续发展。
