Dr. Fakhoury is from Lake Erie College of Osteopathic Medicine, Bradenton, Florida. Dr. Urban is from Prime West Consortium, Newport Beach, California. Drs. Ettefagh and Nami are from Island Dermatology, Newport Beach.
Cutis. 2024 May;113(5):E32-E34. doi: 10.12788/cutis.1023.
Folliculitis decalvans (FD) is a rare primary neutrophilic cicatricial alopecia that commonly displays resistance to traditional therapies and remains challenging to treat. Currently, data are lacking with recommendations for therapy-recalcitrant FD. A systematic review was conducted to analyze biologics, small molecule inhibitors, tumor necrosis factor (TNF) inhibitors, Janus kinase (JAK) inhibitors, phosphodiesterase 4 (PDE4) inhibitors, and monoclonal antibodies utilized in the treatment of recalcitrant FD.
脱发性毛囊炎（FD）是一种罕见的原发性嗜中性瘢痕性脱发，通常对传统疗法有抵抗力，治疗仍然具有挑战性。目前，对于难治性 FD 的治疗建议缺乏数据。进行了系统评价，以分析生物制剂、小分子抑制剂、肿瘤坏死因子（TNF）抑制剂、Janus 激酶（JAK）抑制剂、磷酸二酯酶 4（PDE4）抑制剂和用于治疗难治性 FD 的单克隆抗体。
