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双侧前臂血友病性假肿瘤:一例独特病例报告

Hemophilic pseudotumor in the bilateral forearms: a unique case report.

作者信息

Alaraj Sami F, Krider Samuel O, Elsayes Ahmed, Bazuaye Eseosa, Garcia Glenn M

机构信息

Diagnostic Radiology, University of Texas Medical Branch, Galveston, USA.

University of Texas Medical Branch, Galveston, USA.

出版信息

Skeletal Radiol. 2025 May;54(5):1109-1117. doi: 10.1007/s00256-024-04760-x. Epub 2024 Jul 23.

Abstract

Hemophilic pseudotumor (HP) is a rarely encountered cystic mass that forms as a result of repeated bleeding from extra-articular soft tissues. HP cases have been previously documented in several locations in the body, most commonly in the femur and pelvis. To date, no upper extremity case involving the bilateral forearms has been reported. The current case involves an adult male with uncontrolled hemophilia who presented with diffuse enlargement of the bilateral forearms with associated pain. Radiographs and magnetic resonance imaging (MRI) were subsequently performed revealing variable aged hemorrhagic, expansile, lytic intramedullary lesions. In keeping with the history, a subsequent radiologic diagnosis of HP was favored, among other differentials, including benign and malignant processes with biopsy confirming the diagnosis. The hemorrhagic masses were surgically excised after initial management with factor VIII replacement. This case details a unique presentation of this pathology in the bilateral forearms and highlights the diagnostic value of radiographs and MRI in diagnosis and management.

摘要

血友病性假肿瘤(HP)是一种罕见的囊性肿物,由关节外软组织反复出血形成。此前已在身体的多个部位记录到HP病例,最常见于股骨和骨盆。迄今为止,尚未有涉及双侧前臂的上肢病例报道。本例患者为一名成年男性,患有无法控制的血友病,表现为双侧前臂弥漫性肿大并伴有疼痛。随后进行了X线片和磁共振成像(MRI)检查,发现有不同时期的出血性、膨胀性、溶骨性髓内病变。结合病史,在包括良性和恶性病变在内的其他鉴别诊断中,倾向于对HP进行放射学诊断,活检证实了该诊断。在最初用凝血因子VIII替代治疗后,手术切除了出血性肿物。本病例详细介绍了这种病变在双侧前臂的独特表现,并强调了X线片和MRI在诊断和治疗中的诊断价值。

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