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携带霍乱毒素和霍乱致病岛的 mimic 弧菌谱系,美国和中国。

Vibrio mimicus Lineage Carrying Cholera Toxin and Vibrio Pathogenicity Island, United States and China.

出版信息

Emerg Infect Dis. 2024 Aug;30(8):1729-1732. doi: 10.3201/eid3008.240252.

DOI:10.3201/eid3008.240252
PMID:39043427
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11286048/
Abstract

Vibrio mimicus bacteria have caused sporadic cases and outbreaks of cholera-like diarrhea throughout the world, but the association of lineages with such events is unexplored. Genomic analyses revealed V. mimicus lineages carrying the virulence factors cholera toxin and toxin coregulated pilus, one of which has persisted for decades in China and the United States.

摘要

类霍乱弧菌已在世界各地引起散发性霍乱样腹泻病例和暴发,但谱系与这些事件的关联尚不清楚。基因组分析显示,类霍乱弧菌谱系携带霍乱毒素和毒素调节菌毛等毒力因子,其中一种在中国和美国已经存在了几十年。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e206/11286048/943ffb7f17c3/24-0252-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e206/11286048/943ffb7f17c3/24-0252-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e206/11286048/943ffb7f17c3/24-0252-F.jpg

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本文引用的文献

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Emerg Infect Dis. 2023 Oct;29(10):2141-2144. doi: 10.3201/eid2910.230486.
2
Vibrio Pathogenicity Island-1: The Master Determinant of Cholera Pathogenesis.弧菌致病性岛 1:霍乱发病机制的主要决定因素。
Front Cell Infect Microbiol. 2020 Oct 6;10:561296. doi: 10.3389/fcimb.2020.561296. eCollection 2020.
3
Complete genome analysis of strain SCCF01, a highly virulent isolate from the freshwater catfish.
一株淡水鲶鱼高毒力分离株 SCCF01 的全基因组分析。
Virulence. 2020 Dec;11(1):23-31. doi: 10.1080/21505594.2019.1702797.
4
Vibrio mimicus infection associated with crayfish consumption, Spokane, Washington, 2010.与食用小龙虾相关的 mimic 弧菌感染,华盛顿州斯波坎市,2010 年。
J Food Prot. 2012 Apr;75(4):762-4. doi: 10.4315/0362-028X.JFP-11-410.
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Importation of the major pilin TcpA gene and frequent recombination drive the divergence of the Vibrio pathogenicity island in Vibrio cholerae.霍乱弧菌中主要菌毛蛋白TcpA基因的导入和频繁重组推动了霍乱弧菌致病岛的分化。
FEMS Microbiol Lett. 2008 Dec;289(2):210-8. doi: 10.1111/j.1574-6968.2008.01385.x.
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An incidence of large foodborne outbreak associated with Vibrio mimicus.一起与拟态弧菌相关的大型食源性疾病暴发事件。
Eur J Clin Microbiol Infect Dis. 2009 Apr;28(4):421-4. doi: 10.1007/s10096-008-0639-7. Epub 2008 Oct 17.